ID Q0VFI1_XENTR Unreviewed; 198 AA.
AC Q0VFI1;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=DIRAS family GTP binding RAS like 1 {ECO:0000313|Ensembl:ENSXETP00000112810};
DE SubName: Full=DIRAS family, GTP-binding RAS-like 1 {ECO:0000313|EMBL:AAI18821.1};
DE SubName: Full=GTP-binding protein Di-Ras1 {ECO:0000313|RefSeq:NP_001072780.1, ECO:0000313|RefSeq:XP_031758094.1, ECO:0000313|RefSeq:XP_031758103.1};
GN Name=diras1 {ECO:0000313|EMBL:AAI18821.1,
GN ECO:0000313|Ensembl:ENSXETP00000112810,
GN ECO:0000313|RefSeq:NP_001072780.1, ECO:0000313|RefSeq:XP_031758094.1,
GN ECO:0000313|RefSeq:XP_031758103.1,
GN ECO:0000313|Xenbase:XB-GENE-489505};
GN Synonyms=di-ras1 {ECO:0000313|RefSeq:NP_001072780.1,
GN ECO:0000313|RefSeq:XP_031758094.1, ECO:0000313|RefSeq:XP_031758103.1},
GN gbts1 {ECO:0000313|RefSeq:NP_001072780.1,
GN ECO:0000313|RefSeq:XP_031758094.1, ECO:0000313|RefSeq:XP_031758103.1},
GN rig {ECO:0000313|RefSeq:NP_001072780.1,
GN ECO:0000313|RefSeq:XP_031758094.1, ECO:0000313|RefSeq:XP_031758103.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:AAI18821.1};
RN [1] {ECO:0000313|RefSeq:NP_001072780.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAI18821.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain {ECO:0000313|EMBL:AAI18821.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSXETP00000112810}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000112810};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [4] {ECO:0000313|Ensembl:ENSXETP00000112810}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2021) to UniProtKB.
RN [5] {ECO:0000313|RefSeq:NP_001072780.1, ECO:0000313|RefSeq:XP_031758094.1}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_031758094.1,
RC ECO:0000313|RefSeq:XP_031758103.1};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_031758094.1,
RC ECO:0000313|RefSeq:XP_031758103.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; BC118820; AAI18821.1; -; mRNA.
DR RefSeq; NP_001072780.1; NM_001079312.1.
DR RefSeq; XP_031758094.1; XM_031902234.1.
DR RefSeq; XP_031758103.1; XM_031902243.1.
DR DNASU; 780240; -.
DR Ensembl; ENSXETT00000113899; ENSXETP00000117774; ENSXETG00000047508.
DR Ensembl; ENSXETT00000115945; ENSXETP00000112810; ENSXETG00000047508.
DR GeneID; 780240; -.
DR KEGG; xtr:780240; -.
DR AGR; Xenbase:XB-GENE-489505; -.
DR CTD; 148252; -.
DR Xenbase; XB-GENE-489505; diras1.
DR OMA; LGPIYQL; -.
DR OrthoDB; 8685at2759; -.
DR Proteomes; UP000008143; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR InterPro; IPR020849; Small_GTPase_Ras-type.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR24070:SF213; GTP-BINDING PROTEIN DI-RAS1; 1.
DR PANTHER; PTHR24070; RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS51420; RHO; 1.
PE 2: Evidence at transcript level;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143}.
SQ SEQUENCE 198 AA; 22483 MW; 38007C0C92CB8FC3 CRC64;
MPEQSNDYRV VVFGAGGVGK SSLVLRFVKG TFRDTYIPTI EDTYRQVISC DKSVCTLQIT
DTTGSHQFPA MQRLSISKGH AFILVFSVTS KQSIEELKPI YQQILQIKGS IENIPVMLVG
NKCDETQREV DTKEVEALAK EWKCAFMETS AKMNYNVKEL FQELLNLEKR RNMSLNIDGK
RSSKQKRAEK IKGKCSIM
//
