ID Q0VPU3_ALCBS Unreviewed; 579 AA.
AC Q0VPU3;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Heavy metal RND efflux membrane fusion protein,CzcB family {ECO:0000313|EMBL:CAL16805.1};
GN Name=czcB2 {ECO:0000313|EMBL:CAL16805.1};
GN OrderedLocusNames=ABO_1357 {ECO:0000313|EMBL:CAL16805.1};
OS Alcanivorax borkumensis (strain ATCC 700651 / DSM 11573 / NCIMB 13689 /
OS SK2).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Alcanivoracaceae; Alcanivorax.
OX NCBI_TaxID=393595 {ECO:0000313|EMBL:CAL16805.1, ECO:0000313|Proteomes:UP000008871};
RN [1] {ECO:0000313|EMBL:CAL16805.1, ECO:0000313|Proteomes:UP000008871}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700651 / DSM 11573 / NCIMB 13689 / SK2
RC {ECO:0000313|Proteomes:UP000008871};
RX PubMed=16878126; DOI=10.1038/nbt1232;
RA Schneiker S., Martins dos Santos V.A.P., Bartels D., Bekel T., Brecht M.,
RA Buhrmester J., Chernikova T.N., Denaro R., Ferrer M., Gertler C.,
RA Goesmann A., Golyshina O.V., Kaminski F., Khachane A.N., Lang S., Linke B.,
RA McHardy A.C., Meyer F., Nechitaylo T., Puehler A., Regenhardt D., Rupp O.,
RA Sabirova J.S., Selbitschka W., Yakimov M.M., Timmis K.N., Vorhoelter F.-J.,
RA Weidner S., Kaiser O., Golyshin P.N.;
RT "Genome sequence of the ubiquitous hydrocarbon-degrading marine bacterium
RT Alcanivorax borkumensis.";
RL Nat. Biotechnol. 24:997-1004(2006).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; AM286690; CAL16805.1; -; Genomic_DNA.
DR RefSeq; WP_011588639.1; NC_008260.1.
DR AlphaFoldDB; Q0VPU3; -.
DR STRING; 393595.ABO_1357; -.
DR KEGG; abo:ABO_1357; -.
DR eggNOG; COG0845; Bacteria.
DR eggNOG; COG5569; Bacteria.
DR HOGENOM; CLU_018816_13_1_6; -.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000008871; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 6.10.140.730; -; 1.
DR Gene3D; 2.40.50.320; Copper binding periplasmic protein CusF; 2.
DR InterPro; IPR021647; CusF_Ec.
DR InterPro; IPR042230; CusF_sf.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR045800; HMBD.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30097; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR PANTHER; PTHR30097:SF15; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR Pfam; PF11604; CusF_Ec; 2.
DR Pfam; PF16576; HlyD_D23; 1.
DR Pfam; PF19335; HMBD; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008871}.
FT DOMAIN 54..80
FT /note="Heavy metal binding"
FT /evidence="ECO:0000259|Pfam:PF19335"
FT DOMAIN 117..324
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 579 AA; 62469 MW; CAD990672DA52651 CRC64;
MNIKRNALIG LAASLLLLAG IYLGRYVTPS QSSISMAMDS GETNSKADEK EVLYWYDPMY
PQQHFDEPGP SPFMDMELVP RYANGGDDSD QPTVRIDAAM VQNLGIRSAS VVVAQSQSQL
DVTGLIAYND RALTRLQSPA PSFVDKVWPL AEGDTISSGQ PLMQLRVPAW TGAQHEWLAV
LGSGNNELIV AGRERLLSLG MPASLIRSIE RQRKPLETWT VTAPHDGVIR SLNARAGMTL
SAGAPVAEIQ SLNPVWVEIA VPERQLGQVS SGNAVDVTVQ GVKPALREGQ VADILPLVDQ
SSRTVPVRVT LSNDEGDLRP GMSAQVRIHG EATQKALAVP TAALLHTGKR SLVMLDEGEG
RYRPQAVLPG GELGDQTLIL AGLKEEQKVV VSGQFLLDSE ASLQGIAVQE LAMSDETEMM
NALHYAEGVV EQLNGSKIML DHGPFKSLSM PAMTMRFNLA NEQVGKGISV GDRVRIGIRD
TDKGLIVERL EKQVAEQKDT QVNSLHYAEG VIEGLSDGKV KLKHGPFKTL GMPGMTMRFR
LASEQVASDI AVGDRVRVGV KDTDNGLTVV SLDKQEVAP
//
