ID Q101Z7_9CALI Unreviewed; 94 AA.
AC Q101Z7;
DT 22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT 22-AUG-2006, sequence version 1.
DT 08-NOV-2023, entry version 61.
DE SubName: Full=RNA polymerase {ECO:0000313|EMBL:AAZ99199.1};
DE Flags: Fragment;
OS Human calicivirus NV/GII/Stockholm/0686/2001/SE.
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
OX NCBI_TaxID=342925 {ECO:0000313|EMBL:AAZ99199.1};
RN [1] {ECO:0000313|EMBL:AAZ99199.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NV/GII/Stockholm/0686/2001/SE {ECO:0000313|EMBL:AAZ99199.1};
RX PubMed=18304864; DOI=10.1016/j.jcv.2007.12.012;
RA Johansen K., Mannerqvist K., Allard A., Andersson Y., Burman L.G.,
RA Dillner L., Hedlund K.O., Jonsson K., Kumlin U., Leitner T., Lysen M.,
RA Thorhagen M., Tiveljung-Lindell A., Wahlstrom C., Zweygberg-Wirgart B.,
RA Widell A.;
RT "Norovirus strains belonging to the GII.4 genotype dominate as a cause of
RT nosocomial outbreaks of viral gastroenteritis in Sweden 1997--2005. Arrival
RT of new variants is associated with large nation-wide epidemics.";
RL J. Clin. Virol. 42:129-134(2008).
CC -!- FUNCTION: Viral genome-linked protein is covalently linked to the 5'-
CC end of the positive-strand, negative-strand genomic RNAs and subgenomic
CC RNA. Acts as a genome-linked replication primer. May recruit ribosome
CC to viral RNA thereby promoting viral proteins translation.
CC {ECO:0000256|ARBA:ARBA00025359}.
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DR EMBL; DQ104039; AAZ99199.1; -; Genomic_RNA.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001205; RNA-dir_pol_C.
DR InterPro; IPR007094; RNA-dir_pol_PSvirus.
DR Pfam; PF00680; RdRP_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50507; RDRP_SSRNA_POS; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}.
FT DOMAIN 1..94
FT /note="RdRp catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50507"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAZ99199.1"
FT NON_TER 94
FT /evidence="ECO:0000313|EMBL:AAZ99199.1"
SQ SEQUENCE 94 AA; 10132 MW; F12E37B78D8BFC98 CRC64;
SRWDSTQQRA VLAAALEIMV KFSSEPHLAQ VVAEDLLSPS VVDVGDFKIS INEGLPSGVP
CTSQWNSIAH WLLTLCALSE VTNLSPDIIQ ANSL
//
