ID Q10DR2_ORYSJ Unreviewed; 1748 AA.
AC Q10DR2;
DT 22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT 22-AUG-2006, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE RecName: Full=RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012493};
DE EC=2.7.7.49 {ECO:0000256|ARBA:ARBA00012493};
GN OrderedLocusNames=LOC_Os03g51310 {ECO:0000313|EMBL:ABF98607.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947 {ECO:0000313|EMBL:ABF98607.1};
RN [1] {ECO:0000313|EMBL:ABF98607.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG Rice Chromosome 3 Sequencing Consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S., Luo M.,
RA Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G.,
RA Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [2] {ECO:0000313|EMBL:ABF98607.1}
RP NUCLEOTIDE SEQUENCE.
RA Buell R., Wing R.A., McCombie W.A., Ouyang S.;
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DP000009; ABF98607.1; -; Genomic_DNA.
DR iPTMnet; Q10DR2; -.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd09279; RNase_HI_like; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR005162; Retrotrans_gag_dom.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF03732; Retrotrans_gag; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF00665; rve; 1.
DR Pfam; PF00078; RVT_1; 1.
DR Pfam; PF13456; RVT_3; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 2.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 1635..1748
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 120..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 364..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 441..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1041..1210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1447..1503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..143
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..190
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..410
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 441..459
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1180..1210
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1748 AA; 191164 MW; AC28BAE85EBF05F3 CRC64;
MAEQAKAHNL SPSVSGDDGE PNPRRRARTP PPPPRQSPRR EEALERVEGS ATSTSTGDGE
GRRDGERRLL VYGDGSTPQG ALQAAGALLR HPPIVPDPEA PAQRWLDDVA NLVMTARQRL
GAGGRSSATK TSGAATTGSV SSRRRARRAA AVARHSAATP SSAPPTQEDL RGGPDARISI
ERRRNGRRAA HATEGASSSG VSHQHGRGDQ PSVPPVGGVG CRAFVASLRN VRWPPRFRPT
IAEKYDGSVN PAEFLQVYTT GIEAAGGDDR VMANFFPMAL KGQARGWLMN LPPASVHSWE
DLCQQFTMNF QGTYPRPGEE ADLHAVQRRD DESLRSYIQR FCQVRNTIPC IPAHAVIYAF
RGGRHDRRRK KRSAHSDDEG HVLAVEGASR ATRKGRPASD KKKEAGAPSR ERPTGKWCIV
HNTSLHDLAD CRAVKSLAER TRKWEEERRQ ERREGKSPAV PSGNRRSEAK QKAPAEDIDD
GDDDLGFQEP GATIATVDGG ACAHVSRRSL KAMKRELLAA APTHEATRRA RWSEVALTFD
QTDHPPCVAR GGQIAMVVSP TVCNVKLGRV LIDGGAALNI LSPAAFDAIK APGMVLRPSQ
PIIGVTPGHT WPLGHIDLPV TFGGSANFRT ERVNFDVADL RLPYNAVLGR PALVKFMAAV
HYAYLQMKMP GPGGPISVHG DLKVALACME QRADHLTAAS KPEGGDERLG TSAPAAPRQR
IVTCDEVPED ALVSFLRANA DVFAWRPTDM PGVPREVIEH RLAVRSGARP VRQKVRRQAP
ERQAFIREEV ARLLEAGFIR EVIHPEWLAN PVVVPKVNGK LRMCIDYTDL NKACPKDPYP
LPRIDQIVDS TAGCDLLCFL DAYSGYHQIR MAREDEEKTA FITPIGTYCY TTMPFGLKNA
GPTFQRTTRI SLGSQIGRNV EAYVDDLVVK TRNQETLLSD LAETFESLRS ARIKLNPDKC
VFGVPAGKLL GFLVSAPGIE ANPEKIRAIE RMRPPSKLRD LKAYLSSPPV LVAPEPIEPL
LLYLAATPQV VSAALVVERD EDNPHSAHPH PVLAWPGREQ GGEAPEPNGG PRPPTTGAGP
LPACQTVPGA PDPQDGPRAT AGRPHLSPSD PEANPVPTRP GREQGEEAPK PNGGLRPLTT
GVGPLPACPT TPGAPDPQDG PEATVGRPPL SSSDPEVVGT EDECTPRGRL DKERPRDVAP
SEEDRPHRKV QRPIYFVSEA LRDAKTRYPQ AQKMLYAILM ASRKLRHYFQ AHRVTVVTSY
PLGQILHNRE GTRRVVKWAI ELSEFDLHFE PRHAIKSQAF ADFVAEWTPA PEPVSVPEAS
SGPSQLPHTA HWVMQFDGSL SLQGAGAGVT LTSPNGDVLR YLVRLDFRAT NNMAEYKGLL
AGLRVAAGLG IRRLLVLGDS QLVVNQVCKE YRCSDPQMDA YVRQVRRMER HFDGIELRHV
PRRDNTVGDE LSRLASSRAQ TPPGAFEERL AQPSARPDPL GETDAPDRPP MPVGVQASGP
EGSAPSSLRL IAWIAEIQAY LTDKTLPEDR EGSERVQRIS KRYVLVEGTL YRRAANGILL
KCIPREQGVE LLADIHEGEC GAHSASRTLV GKAFRQGFYW PTTLNDAVDL VRRCRACQFH
AKQIHQPAQA LQIIPLSWPF AVWGLDILGP FRRAPGGFEY LYVAIDKFTK WPEAYPVVKI
DKHSALKFIK GITARFGVPN RIITDNGTQF TSELFGDYCE DMGIKLCFAS PAHPRSNGQV
ERANAEIL
//
