ID Q12UU5_METBU Unreviewed; 462 AA.
AC Q12UU5;
DT 22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT 22-AUG-2006, sequence version 1.
DT 24-JAN-2024, entry version 99.
DE SubName: Full=PleD-like multisensor signal transduction histidine kinase {ECO:0000313|EMBL:ABE52781.1};
GN OrderedLocusNames=Mbur_1899 {ECO:0000313|EMBL:ABE52781.1};
OS Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 /
OS ACE-M).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanococcoides.
OX NCBI_TaxID=259564 {ECO:0000313|EMBL:ABE52781.1, ECO:0000313|Proteomes:UP000001979};
RN [1] {ECO:0000313|Proteomes:UP000001979}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6242 / NBRC 107633 / OCM 468 / ACE-M
RC {ECO:0000313|Proteomes:UP000001979};
RX PubMed=19404327; DOI=10.1038/ismej.2009.45;
RA Allen M.A., Lauro F.M., Williams T.J., Burg D., Siddiqui K.S.,
RA De Francisci D., Chong K.W., Pilak O., Chew H.H., De Maere M.Z., Ting L.,
RA Katrib M., Ng C., Sowers K.R., Galperin M.Y., Anderson I.J., Ivanova N.,
RA Dalin E., Martinez M., Lapidus A., Hauser L., Land M., Thomas T.,
RA Cavicchioli R.;
RT "The genome sequence of the psychrophilic archaeon, Methanococcoides
RT burtonii: the role of genome evolution in cold adaptation.";
RL ISME J. 3:1012-1035(2009).
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DR EMBL; CP000300; ABE52781.1; -; Genomic_DNA.
DR RefSeq; WP_011499924.1; NC_007955.1.
DR AlphaFoldDB; Q12UU5; -.
DR STRING; 259564.Mbur_1899; -.
DR GeneID; 3997691; -.
DR KEGG; mbu:Mbur_1899; -.
DR HOGENOM; CLU_000445_114_72_2; -.
DR OrthoDB; 9652at2157; -.
DR Proteomes; UP000001979; Chromosome.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00130; PAS; 1.
DR CDD; cd17538; REC_D1_PleD-like; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR011495; Sig_transdc_His_kin_sub2_dim/P.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065:SF23; SENSOR HISTIDINE KINASE PDTAS-RELATED; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07568; HisKA_2; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ABE52781.1};
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW Transferase {ECO:0000313|EMBL:ABE52781.1}.
FT DOMAIN 8..123
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 211..263
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 271..462
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT MOD_RES 56
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 462 AA; 53116 MW; 776A6270F57BC0C2 CRC64;
MQNNELPRIL VVDDDQKNVE LMEAYLSPDY ETIPAYRGKE ALEILEKDEI DLVLLDVMMP
DMKGYEVCIK LKEDIKTQFI PVIIVSALSR KKDRIQGLEA GADEFLTKPV DQIELKTRVK
SLLRLKELYD RNIHEKELAN KYFDTADVML IVIDPDHKIK LINKKGCKIM ACEEMTLIGT
DFFNTMVPER FRESGIEDFY RFISGNISGL ENFEAPLLRL DGEERIVNWH NTLLKNKNGK
ITGMLSSGED ITERKRVEEA LIETEEIHEK EIHHRIKNNL QIIASLLDLE ASNFTDPQVI
NAFKESRDRI HSISIAHEEL YRSRDMTNVA FQDYAKDVTN YLYQMNGQQA KNIKLRMEVE
DTLLSVDRAI HLGLILNELI VNCFKYAFPD GKGNISIVFH RKDDQFTLIV ADNGIGIQKE
IEIGNTKTLG MQLVNELVKQ IGGNIHIDRS NGTKVTITFK DK
//
