ID Q15423_HUMAN Unreviewed; 64 AA.
AC Q15423;
DT 01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1996, sequence version 1.
DT 22-FEB-2023, entry version 84.
DE RecName: Full=Serum amyloid A protein {ECO:0000256|RuleBase:RU000539};
DE Flags: Fragment;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|EMBL:CAA35808.1};
RN [1] {ECO:0000313|EMBL:CAA35808.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Liver {ECO:0000313|EMBL:CAA35808.1};
RX PubMed=1971508;
RA Steinkasserer A., Weiss E.H., Schwaeble W., Linke R.P.;
RT "Heterogeneity of human serum amyloid A protein. Five different variants
RT from one individual demonstrated by cDNA sequence analysis.";
RL Biochem. J. 268:187-193(1990).
CC -!- FUNCTION: Major acute phase reactant. Apolipoprotein of the HDL
CC complex. {ECO:0000256|RuleBase:RU000539}.
CC -!- SIMILARITY: Belongs to the SAA family. {ECO:0000256|ARBA:ARBA00007745,
CC ECO:0000256|RuleBase:RU000539}.
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DR EMBL; X51443; CAA35808.1; -; mRNA.
DR AlphaFoldDB; Q15423; -.
DR PeptideAtlas; Q15423; -.
DR GO; GO:0034364; C:high-density lipoprotein particle; IEA:UniProtKB-UniRule.
DR GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.132.110; Serum amyloid A protein; 1.
DR InterPro; IPR000096; Serum_amyloid_A.
DR Pfam; PF00277; SAA; 1.
DR PRINTS; PR00306; SERUMAMYLOID.
DR SMART; SM00197; SAA; 1.
PE 2: Evidence at transcript level;
KW Acute phase {ECO:0000256|ARBA:ARBA00022486, ECO:0000256|RuleBase:RU000539};
KW HDL {ECO:0000256|ARBA:ARBA00022850, ECO:0000256|RuleBase:RU000539}.
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAA35808.1"
FT NON_TER 64
FT /evidence="ECO:0000313|EMBL:CAA35808.1"
SQ SEQUENCE 64 AA; 7079 MW; 057D6C9B0BE06238 CRC64;
VFCSLVLGVS SRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP
GGLG
//
