ID Q17W14_HELAH Unreviewed; 676 AA.
AC Q17W14;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE RecName: Full=Sulfatase N-terminal domain-containing protein {ECO:0000259|Pfam:PF00884};
GN OrderedLocusNames=Hac_1434 {ECO:0000313|EMBL:CAK00162.1};
OS Helicobacter acinonychis (strain Sheeba).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=382638 {ECO:0000313|EMBL:CAK00162.1, ECO:0000313|Proteomes:UP000000775};
RN [1] {ECO:0000313|EMBL:CAK00162.1, ECO:0000313|Proteomes:UP000000775}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Sheeba {ECO:0000313|EMBL:CAK00162.1,
RC ECO:0000313|Proteomes:UP000000775};
RX PubMed=16789826; DOI=10.1371/journal.pgen.0020120;
RA Eppinger M., Baar C., Linz B., Raddatz G., Lanz C., Keller H., Morelli G.,
RA Gressmann H., Achtman M., Schuster S.C.;
RT "Who ate whom? Adaptive Helicobacter genomic changes that accompanied a
RT host jump from early humans to large felines.";
RL PLoS Genet. 2:1097-1110(2006).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AM260522; CAK00162.1; -; Genomic_DNA.
DR RefSeq; WP_011578252.1; NC_008229.1.
DR AlphaFoldDB; Q17W14; -.
DR STRING; 382638.Hac_1434; -.
DR KEGG; hac:Hac_1434; -.
DR eggNOG; COG1368; Bacteria.
DR HOGENOM; CLU_027564_0_0_7; -.
DR OrthoDB; 9760224at2; -.
DR BioCyc; HACI382638:HAC_RS06105-MONOMER; -.
DR Proteomes; UP000000775; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd16015; LTA_synthase; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR47371; LIPOTEICHOIC ACID SYNTHASE; 1.
DR PANTHER; PTHR47371:SF3; PHOSPHOGLYCEROL TRANSFERASE I; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 292..581
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
SQ SEQUENCE 676 AA; 77348 MW; C1C087E045C06194 CRC64;
MKPLSSALFS LFLKGFYFTF FMSLLFVFNR IGFILYTGYY KHALKNPVFD EIIKTLLNGA
RYDNRVVSSL AILFIIIGLL GLLIPKHQTK MLNAVAYFSI AIILFLNIAN IVYYGIYGNV
FDENLLEFLH EDTLTILKMS GEYPILSSFS LFVIFSVLTS FIYLKLQDTL FKQKNIYPTT
KPLKTFILFI LFSLTQMFYI NAQLSFVGAS LDLSIEPAKD PFLMKITPGA FRSLYLLVRN
YRQSHNLKFS DFSKETPLEV AKNYFHLKEN PSNNLYNLLS QTSYNDSNQT IKHVFYIVSE
SLSSWHFDQK FDSIGLTSAL QNLVKKEHAY MLSSFIESAP RTVKSLDVQI TGLPYINDNN
LINSGVILPS FPMAIGNIMK TLGYRNNFYY GGSGIWNKLD SFTKKQGFHA LYFNNHLLEF
AKNKPYPKPI ESNWGVHDNI LFDYILENTN PNEKTFSMVM TLSNHAIKNV NLKAFGVPLE
KIQNFVEKTP KSQNLPDANS LGHIYWYDKV VVNFIKKASQ KFPSSLFIIT GDHFDRSYEY
AKNDLYITKS VPLIVFAPTL KPKIISQVGS HLDIAPSIIE LVAPKGFPFV SFGKPLFSNN
ATNPPSHPNY ALGYEAIATK DYFYNPSVGL RYLNENHKDQ NDKQNDKIEA SKFYQQLESL
KALSYYLLYH GANLSQ
//
