ID Q189P2_CLOD6 Unreviewed; 223 AA.
AC Q189P2;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 104.
DE SubName: Full=Regulator of K+ conductance {ECO:0000313|EMBL:CAJ67530.1};
GN OrderedLocusNames=CD630_06970 {ECO:0000313|EMBL:CAJ67530.1};
OS Clostridioides difficile (strain 630) (Peptoclostridium difficile).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC Clostridioides.
OX NCBI_TaxID=272563 {ECO:0000313|EMBL:CAJ67530.1, ECO:0000313|Proteomes:UP000001978};
RN [1] {ECO:0000313|EMBL:CAJ67530.1, ECO:0000313|Proteomes:UP000001978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=630 {ECO:0000313|EMBL:CAJ67530.1,
RC ECO:0000313|Proteomes:UP000001978};
RX PubMed=16804543; DOI=10.1038/ng1830;
RA Sebaihia M., Wren B.W., Mullany P., Fairweather N.F., Minton N.,
RA Stabler R., Thomson N.R., Roberts A.P., Cerdeno-Tarraga A.M., Wang H.,
RA Holden M.T.G., Wright A., Churcher C., Quail M.A., Baker S., Bason N.,
RA Brooks K., Chillingworth T., Cronin A., Davis P., Dowd L., Fraser A.,
RA Feltwell T., Hance Z., Holroyd S., Jagels K., Moule S., Mungall K.,
RA Price C., Rabbinowitsch R., Sharp S., Simmonds M., Steven K., Unwin L.,
RA Whithead S., Dupuy B., Dougan G., Barrell B.and.Parkhill.J.;
RT "The multidrug-resistant human pathogen Clostridium difficile has a highly
RT mobile, mosaic genome.";
RL Nat. Genet. 38:779-786(2006).
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DR EMBL; AM180355; CAJ67530.1; -; Genomic_DNA.
DR RefSeq; WP_003418257.1; NZ_JAUPES010000005.1.
DR RefSeq; YP_001087173.1; NC_009089.1.
DR AlphaFoldDB; Q189P2; -.
DR SMR; Q189P2; -.
DR STRING; 272563.CD630_06970; -.
DR EnsemblBacteria; CAJ67530; CAJ67530; CD630_06970.
DR GeneID; 66353199; -.
DR KEGG; cdf:CD630_06970; -.
DR KEGG; pdc:CDIF630_00811; -.
DR PATRIC; fig|272563.120.peg.717; -.
DR eggNOG; COG0569; Bacteria.
DR OrthoDB; 9776294at2; -.
DR PhylomeDB; Q189P2; -.
DR BioCyc; PDIF272563:G12WB-807-MONOMER; -.
DR Proteomes; UP000001978; Chromosome.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR43833:SF7; KTR SYSTEM POTASSIUM UPTAKE PROTEIN C; 1.
DR PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR Pfam; PF02080; TrkA_C; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR PROSITE; PS51202; RCK_C; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001978}.
FT DOMAIN 3..124
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 134..218
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 223 AA; 24264 MW; 19F76D31233504E9 CRC64;
MKQYIVIGCG RFGSSVASTM HLLGHQVMAI DKNEDSVQSI SDKVTHSLIV DVTDEQALRS
LGLGNFDVAV VAIGSDIRAS IMATLIAKEM GVELIICKAK DELQAKVLYK IGADRVVFPE
RDMGVRVAHN LVSDNILDHI ELDPEYSIVE IVTPNSWVGK TLIELELRAR YEITVLAIKT
GKNINVTPSP DEELTAGSIL VIIGQNTSIT AITSGNKGII RRR
//
