ID Q18HY6_HALWD Unreviewed; 356 AA.
AC Q18HY6;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=DUF21/CBS domain protein {ECO:0000313|EMBL:CAJ52393.1};
GN OrderedLocusNames=HQ_2269A {ECO:0000313|EMBL:CAJ52393.1};
OS Haloquadratum walsbyi (strain DSM 16790 / HBSQ001).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloquadratum.
OX NCBI_TaxID=362976 {ECO:0000313|EMBL:CAJ52393.1, ECO:0000313|Proteomes:UP000001975};
RN [1] {ECO:0000313|EMBL:CAJ52393.1, ECO:0000313|Proteomes:UP000001975}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16790 / HBSQ001 {ECO:0000313|Proteomes:UP000001975};
RX PubMed=16820047; DOI=10.1186/1471-2164-7-169;
RA Bolhuis H.H., Palm P.P., Wende A.W., Falb M.M., Rampp M.M.,
RA Rodriguez-Valera F.F., Pfeiffer F.F., Oesterhelt D.D.;
RT "The genome of the square archaeon Haloquadratum walsbyi: life at the
RT limits of water activity.";
RL BMC Genomics 7:169-169(2006).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AM180088; CAJ52393.1; -; Genomic_DNA.
DR RefSeq; WP_011571525.1; NC_008212.1.
DR AlphaFoldDB; Q18HY6; -.
DR STRING; 362976.HQ_2269A; -.
DR GeneID; 4192838; -.
DR KEGG; hwa:HQ_2269A; -.
DR eggNOG; arCOG00626; Archaea.
DR HOGENOM; CLU_015237_4_0_2; -.
DR Proteomes; UP000001975; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR PANTHER; PTHR43099:SF5; INTEGRAL MEMBRANE PROTEIN-RELATED; 1.
DR PANTHER; PTHR43099; UPF0053 PROTEIN YRKA; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF01595; CNNM; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51371; CBS; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001975};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 3..200
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 290..349
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 356 AA; 39267 MW; 07486FE496282066 CRC64;
MMEPLEIGLR IFGGIILILV NAYFVAIEFA LTRVRQYPKS EFDTPGLELA WEMTNDLEFY
LTTCQVWISA TSIALGIIAE PGLAALIEPV FENTTLASVG AGSLLGFLII NLVHLTHGEQ
TPTYLGVERS KQVAQYGARV LYWFAKILAP AIWVGDSVAK GTLGLFGIEM TQAWTETEKE
VIETRADLRT RLGSVLEQGE LPADRREEIM NALTIGEQSV REIMISADDI ISLSTEDSPE
SNFQKLEEYP HTRYPLIGGE LSDFHGIVYS PALFSHREQL SNDNDALIEL AAPTMTLSPD
TDVSDAIDQF QTEQQEMGLV IEDGEVTGLV TVTDLLETII GDIEDPLDQD NPNVLS
//
