ID Q1D9D6_MYXXD Unreviewed; 448 AA.
AC Q1D9D6;
DT 11-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=PmbA/tldD protein {ECO:0000313|EMBL:ABF92013.1};
GN OrderedLocusNames=MXAN_2518 {ECO:0000313|EMBL:ABF92013.1};
OS Myxococcus xanthus (strain DK1622).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Myxococcus.
OX NCBI_TaxID=246197 {ECO:0000313|EMBL:ABF92013.1, ECO:0000313|Proteomes:UP000002402};
RN [1] {ECO:0000313|EMBL:ABF92013.1, ECO:0000313|Proteomes:UP000002402}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DK1622 {ECO:0000313|Proteomes:UP000002402};
RX PubMed=17015832; DOI=10.1073/pnas.0607335103;
RA Goldman B.S., Nierman W.C., Kaiser D., Slater S.C., Durkin A.S.,
RA Eisen J.A., Ronning C.M., Barbazuk W.B., Blanchard M., Field C.,
RA Halling C., Hinkle G., Iartchuk O., Kim H.S., Mackenzie C., Madupu R.,
RA Miller N., Shvartsbeyn A., Sullivan S.A., Vaudin M., Wiegand R.,
RA Kaplan H.B.;
RT "Evolution of sensory complexity recorded in a myxobacterial genome.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15200-15205(2006).
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
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DR EMBL; CP000113; ABF92013.1; -; Genomic_DNA.
DR RefSeq; WP_011552589.1; NC_008095.1.
DR AlphaFoldDB; Q1D9D6; -.
DR STRING; 246197.MXAN_2518; -.
DR EnsemblBacteria; ABF92013; ABF92013; MXAN_2518.
DR GeneID; 41359895; -.
DR KEGG; mxa:MXAN_2518; -.
DR eggNOG; COG0312; Bacteria.
DR HOGENOM; CLU_026425_0_0_7; -.
DR OrthoDB; 9803618at2; -.
DR Proteomes; UP000002402; Chromosome.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR047657; PmbA.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR43421; METALLOPROTEASE PMBA; 1.
DR PANTHER; PTHR43421:SF1; METALLOPROTEASE PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19290; PmbA_TldD_2nd; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002402}.
FT DOMAIN 22..86
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 118..222
FT /note="Metalloprotease TldD/E central"
FT /evidence="ECO:0000259|Pfam:PF19290"
FT DOMAIN 229..447
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 448 AA; 47917 MW; A92C9EDA9C52B915 CRC64;
MDYQQLAKRI VQRAKRKGAR QAEAFLEVGR QSSVRVHQGQ IEDLTQSTSK GVGVRVVLKD
RLGFAYTSDF EPSAVDHIVD QALKLAEFSA PSKLNGLPSG KDLGRFGDTG LLFDTKVAEL
PGDWKIKTAL EVEKAARAED SRIIAFNGVG AGDYVSEVYM ASTEGVTGAY SGTYVYLYAA
PVASDGNGLQ TGYWMDYRRF LDDLDGPESI GREATRRAVR MLGAKRVKTQ QVPVLFDPQV
AASFVSDVAG AADGNAVYQK ASLLASLLGK RLAGAHVTLV DDGLMPRGLA TAPFDGEGVP
TRRTPIIEQG VLKSFLYDAF TARKAKARTT GNASRSYNGL PSIGTSNLYL EAGTKSPEEL
LREVDSGFYV TALLGHGTDP VTGELSAGAN GLWIEKGELT HPVQEVTVAG SLLQMLKDLD
GVGSDLQFRS GAVGAPTVRF RQLTVSGE
//
