ID Q1H1J9_METFK Unreviewed; 677 AA.
AC Q1H1J9;
DT 27-JUN-2006, integrated into UniProtKB/TrEMBL.
DT 27-JUN-2006, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=Alpha-amylase {ECO:0000313|EMBL:ABE49638.1};
DE EC=3.2.1.1 {ECO:0000313|EMBL:ABE49638.1};
GN OrderedLocusNames=Mfla_1370 {ECO:0000313|EMBL:ABE49638.1};
OS Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Methylophilaceae; Methylobacillus.
OX NCBI_TaxID=265072 {ECO:0000313|EMBL:ABE49638.1, ECO:0000313|Proteomes:UP000002440};
RN [1] {ECO:0000313|EMBL:ABE49638.1, ECO:0000313|Proteomes:UP000002440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KT / ATCC 51484 / DSM 6875 {ECO:0000313|Proteomes:UP000002440};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Brettin T., Bruce D., Han C., Tapia R., Saunders E., Gilna P., Schmutz J.,
RA Larimer F., Land M., Kyrpides N., Anderson I., Richardson P.;
RT "Complete sequence of Methylobacillus flagellatus KT.";
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 57 family.
CC {ECO:0000256|ARBA:ARBA00006821}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000284; ABE49638.1; -; Genomic_DNA.
DR RefSeq; WP_011479592.1; NC_007947.1.
DR AlphaFoldDB; Q1H1J9; -.
DR STRING; 265072.Mfla_1370; -.
DR CAZy; GH57; Glycoside Hydrolase Family 57.
DR KEGG; mfa:Mfla_1370; -.
DR eggNOG; COG1449; Bacteria.
DR HOGENOM; CLU_026700_0_0_4; -.
DR OrthoDB; 8476at2; -.
DR Proteomes; UP000002440; Chromosome.
DR GO; GO:0004556; F:alpha-amylase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd10793; GH57N_TLGT_like; 1.
DR Gene3D; 2.70.98.10; -; 1.
DR Gene3D; 3.20.110.20; -; 1.
DR InterPro; IPR015179; A-amylase/a-glucTrfase_C.
DR InterPro; IPR015178; A-amylase/a-glucTrfase_central.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR InterPro; IPR004300; Glyco_hydro_57_N.
DR PANTHER; PTHR36306:SF1; 4-ALPHA-GLUCANOTRANSFERASE; 1.
DR PANTHER; PTHR36306; ALPHA-AMYLASE-RELATED-RELATED; 1.
DR Pfam; PF09094; AmyA-A_glucT_m; 1.
DR Pfam; PF09095; AmyA-gluTrfs_C; 1.
DR Pfam; PF03065; Glyco_hydro_57; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Glycosidase {ECO:0000313|EMBL:ABE49638.1};
KW Hydrolase {ECO:0000313|EMBL:ABE49638.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002440}.
FT DOMAIN 23..274
FT /note="Glycoside hydrolase family 57 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03065"
FT DOMAIN 317..395
FT /note="Alpha-amylase/4-alpha-glucanotransferase central"
FT /evidence="ECO:0000259|Pfam:PF09094"
FT DOMAIN 409..662
FT /note="Alpha-amylase/4-alpha-glucanotransferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF09095"
SQ SEQUENCE 677 AA; 76849 MW; A701F9D48420C354 CRC64;
MARSVALLLG VHAHQPVGNF ESVLEDAHAR CYGPFLRVMH EYPAFHFAIH ISGWLLEYML
KHFPQEMALL REMVERGQAE LFGAGFTEPV LASIPVRDRI GQINTLSHFL AEKLGHAPQG
AWLTERVWES AVVPALAEAG IKYVTVDDYH FMCAGKQTDA LNGFYTTEED SRHVDLFPIS
EALRYRMPFS AADEVVGYLE SLAGEGGQDG ELPAAVYFDD IEKFGIWPET YNWVYERGWL
RQFIEGVLNS DVIKPMRYAD YHRQARTKGV VYLPTTSYIE MNEWTLPVPA AHHYADLVAQ
ERQHQRYDVT KPFVRGGIWR NFLMRYPESN WMHKRMLGLS QRYHSLPPDL QNAQMLKALY
EAQANDAYWH GLFGGLYLPH LRRAVYHALI KLEALLDQVE ERPAIEALDL DLDGHDELFI
QNGSLQAVVK LDETAAVVEL DSYALGHNFG DTLTRQPEHY HRKIHATGEH QSHGEGITNP
HEQMGSKHEI LPGDLDTDTY RKALFHDSWL DNGANIQIRY QQDGRPKPEF SGFLPGGDAA
FLRKQYRLEG NALQVTYQAL DVTGVSGRLR VELNLAMPSC DGPAGRFRLQ DDILGGFGQA
LSMDEWQELF LDDDVLGGTL HLRSSVPANY FSYPHCSVSQ SEAGFEKIMQ AVTMVLEWPL
EQLVSGINLH IEFIKNK
//
