ID Q1JFU9_STRPD Unreviewed; 413 AA.
AC Q1JFU9;
DT 13-JUN-2006, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2006, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Transcriptional regulator, Cro/CI family {ECO:0000313|EMBL:ABF34460.1};
GN OrderedLocusNames=MGAS10270_Spy1395 {ECO:0000313|EMBL:ABF34460.1};
OS Streptococcus pyogenes serotype M2 (strain MGAS10270).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=370552 {ECO:0000313|EMBL:ABF34460.1, ECO:0000313|Proteomes:UP000002436};
RN [1] {ECO:0000313|EMBL:ABF34460.1, ECO:0000313|Proteomes:UP000002436}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGAS10270 {ECO:0000313|EMBL:ABF34460.1,
RC ECO:0000313|Proteomes:UP000002436};
RX PubMed=16636287; DOI=10.1073/pnas.0510279103;
RA Beres S.B., Richter E.W., Nagiec M.J., Sumby P., Porcella S.F., DeLeo F.R.,
RA Musser J.M.;
RT "Molecular genetic anatomy of inter- and intraserotype variation in the
RT human bacterial pathogen group A Streptococcus.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:7059-7064(2006).
CC -!- SIMILARITY: Belongs to the plasmid replication initiation factor
CC family. {ECO:0000256|ARBA:ARBA00008374}.
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DR EMBL; CP000260; ABF34460.1; -; Genomic_DNA.
DR RefSeq; WP_020905348.1; NC_008022.1.
DR AlphaFoldDB; Q1JFU9; -.
DR KEGG; sph:MGAS10270_Spy1395; -.
DR HOGENOM; CLU_037938_0_0_9; -.
DR Proteomes; UP000002436; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR003491; REP-like_C.
DR InterPro; IPR040819; Rol_Rep_N.
DR Pfam; PF01381; HTH_3; 1.
DR Pfam; PF02486; Rep_trans; 1.
DR Pfam; PF18106; Rol_Rep_N; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 3: Inferred from homology;
FT DOMAIN 6..71
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 413 AA; 48816 MW; A119B9F50F88E7C3 CRC64;
MNPMYLKKFR KKSGLKQKEF AKCIGISQAM LSQYESGKKK LSLEKFQEMK THFGYLTDND
SSRLQVTIDY VRITLKSVRD LEFFCRNFLH CRFKEFSSVE SKLMNYNHIW KRGDIWIFDY
ADKHDTGNYQ ITLQLSGQGC RQLELLMEQE NFAWLDWLIY LRRSYRDEMN VTRFDLAIDE
LYLGKDRENE HFLLSDMIVK YYHHELAFES LRTWNYIGGG ALNFNDMEEI EQNRQGISLY
FGSRQSEMYF NFYEKRYELA KLEGISVEES LEIFEIWNRY EIRLSQSKAN AVVDEFISGI
PLGEIARGLI NSKIQVYDGK NKYGAFMADQ KWQMMFGGVE PLTFVTRPES YNIERTIRWL
IHQVSDSLAM VSEYDSMIDG DNLQMIINSG EVNERGEKIL ETIRYNLGLD KGA
//
