ID Q1MQX5_LAWIP Unreviewed; 700 AA.
AC Q1MQX5;
DT 30-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 30-MAY-2006, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Type III secretion pore protein {ECO:0000313|EMBL:CAJ54602.1};
GN Name=yscV {ECO:0000313|EMBL:CAJ54602.1};
GN OrderedLocusNames=LI0548 {ECO:0000313|EMBL:CAJ54602.1};
OS Lawsonia intracellularis (strain PHE/MN1-00).
OC Bacteria; Thermodesulfobacteriota; Desulfovibrionia; Desulfovibrionales;
OC Desulfovibrionaceae; Lawsonia.
OX NCBI_TaxID=363253 {ECO:0000313|EMBL:CAJ54602.1, ECO:0000313|Proteomes:UP000002430};
RN [1] {ECO:0000313|EMBL:CAJ54602.1, ECO:0000313|Proteomes:UP000002430}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PHE/MN1-00 {ECO:0000313|EMBL:CAJ54602.1,
RC ECO:0000313|Proteomes:UP000002430};
RA Kaur K., Zhang Q., Beckler D., Munir S., Li L., Kinsley K., Herron L.,
RA Peterson A., May B., Singh S., Gebhart C., Kapur V.;
RT "The complete genome sequence of Lawsonia intracellularis: the causative
RT agent of proliferative enteropathy.";
RL Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835}.
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DR EMBL; AM180252; CAJ54602.1; -; Genomic_DNA.
DR RefSeq; WP_011526631.1; NC_008011.1.
DR AlphaFoldDB; Q1MQX5; -.
DR STRING; 363253.LI0548; -.
DR KEGG; lip:LI0548; -.
DR eggNOG; COG4789; Bacteria.
DR HOGENOM; CLU_015346_3_0_7; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000002430; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR InterPro; IPR006302; T3SS_HrcV.
DR NCBIfam; TIGR01399; hrcV; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR PANTHER; PTHR30161:SF2; INVASION PROTEIN INVA; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002430};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 45..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 334..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 334..351
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 700 AA; 77388 MW; EADE4A564824C160 CRC64;
MSLFAKAQST VGVITRNNDI TMVLLLVTVI ALMIIPLPTP LVDTLIGINM GLSFLIVMMC
MYVKTVLDFS VFPTMLLFTT LFRVGLNITT TRLILLQADA GEIIFIFGEF ALGGNFVVGA
VVFVILTIVQ FLVIAKGAER VAEVGARFTL DAMPGKQMSI DADMRAGVID MEEAQKRRAR
INQESQMYGA MDGAMKFVKG DSIAGMIIAV VNIVGGTIIG VTQHGMAASD ALHVYGILTI
GDGLVSQIPS LLISIAAGIL ITRTGDSAEN VGSQIGEQIF NQPKALLMAG GVVFLIALVP
GFPKIQLFAI SATLAGIGYT LKLIMTNPAP KNAKQSIAKT LEPTTSPSKK SSTEQKESKE
EFSPTVPIIL DISQQMSEEL DYDSLNDELI TLRRVLYFDL GVPFPGINLR ISSKLHDLTY
SLMINEIPIT KGTLEKGMVL ARDTKENLAM LGVEPEEKEK FLPDVESLWV PDSKKALLER
AGITCMTHSR ILAYHLSLVL SRHASNFLGM QETKYLLDKM EERAPDLVRE TTRLLPVQRI
AEIFQRLVQE QISIRDLRSI LEALIEWSPK EKDTVMLTEY VRSALKRQIS YMYSKGQNML
PAVLLDPNVE ETIRKSVRQT SAGAFLALDP ETTQIFMASL KEFASETNLT YTQKPVLITS
MDIRRYVRRL IEGDYYNLPV VSYQELTPEI SVQPVGRIRF
//
