ID Q1PG70_EPOWA Unreviewed; 410 AA.
AC Q1PG70;
DT 16-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2006, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=von Willebrand factor {ECO:0000256|ARBA:ARBA00016619};
DE Flags: Fragment;
GN Name=vWF {ECO:0000313|EMBL:ABE02442.1};
OS Epomophorus wahlbergi (Wahlberg's epauletted fruit bat) (Pteropus
OS wahlbergi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Epomophorini-Myonycterini lineage; Epomophorini; Epomophorus.
OX NCBI_TaxID=58067 {ECO:0000313|EMBL:ABE02442.1};
RN [1] {ECO:0000313|EMBL:ABE02442.1}
RP NUCLEOTIDE SEQUENCE.
RA Giannini N.P., Almeida F.C., Simmons N.B., DeSalle R.;
RT "Phylogenetic relationships of the enigmatic Harpy Fruit Bat,
RT Harpyionycteris (Mammalia: Chiroptera: Pteropodidae).";
RL Am. Mus. Novit. 0:0-0(2006).
CC -!- SUBUNIT: Multimeric. Interacts with F8.
CC {ECO:0000256|ARBA:ARBA00025858}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR EMBL; DQ445691; ABE02442.1; -; Genomic_DNA.
DR GO; GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.
DR CDD; cd01450; vWFA_subfamily_ECM; 2.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR032361; VWA_N2.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR22588; UNCHARACTERIZED; 1.
DR PANTHER; PTHR22588:SF3; VWFA DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00092; VWA; 2.
DR Pfam; PF16164; VWA_N2; 1.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW Blood coagulation {ECO:0000256|ARBA:ARBA00023084};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hemostasis {ECO:0000256|ARBA:ARBA00022696};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 39..215
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 260..410
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABE02442.1"
FT NON_TER 410
FT /evidence="ECO:0000313|EMBL:ABE02442.1"
SQ SEQUENCE 410 AA; 45431 MW; 27F67C0F6DA6ACBA CRC64;
EPIGLEVPPT EVPSSPTTPY VEDTPEPPLH DFYCSKLLDL VFLLDGSNKL SEAEFEVLKV
FVVGMMERLH ISQKRIRVAV VEYHDGSHAY LELRDRKRPS ELRRIASQVK YAGSSVASTS
EVLKYTLFQI FGKVDRPEAS RIVLLLTASQ EPPKLARNLV RYVQGLKKKK VTVVPVGIGP
HANLKQIRLI EKQAPENKAF VLSGVDELEQ RRDEIISYLC DLAPEAPAPT QPPPVAQVTV
GPELLGVLSQ GPRRNSMVLD VVFVLEGSDK IGEANFNRSK EFMEAVIQRM DVSQDSIHVT
VLQYSYVVTV ESTFLEAQSK GDVLQRVREI RFRGGNRTNT GLALQYLSEH SFSTSQGDRE
QAPNLVYMVX GNPASDEIKR MPGDIQVVPI GVGPQADVQE LEGSAGPMPL
//
