ID Q1PHX0_9ENTO Unreviewed; 613 AA.
AC Q1PHX0;
DT 16-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2006, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Genome polyprotein {ECO:0000256|ARBA:ARBA00020107};
DE Flags: Fragment;
OS Poliovirus 1.
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Picornavirales; Picornaviridae; Ensavirinae; Enterovirus; Enterovirus C.
OX NCBI_TaxID=12080 {ECO:0000313|EMBL:ABE02678.1};
RN [1] {ECO:0000313|EMBL:ABE02678.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PV1/04-372/DEU {ECO:0000313|EMBL:ABE02678.1};
RA Vollnberg B., Diedrich S., Schreier E.;
RT "Genetic drift of poliovirus type 1 during 51 months of prolonged
RT intestinal replication in an immunodeficient patient.";
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Interacts with capsid protein VP1 and capsid protein VP3 to
CC form heterotrimeric protomers. {ECO:0000256|ARBA:ARBA00011474}.
CC -!- SIMILARITY: Belongs to the picornaviruses polyprotein family.
CC {ECO:0000256|ARBA:ARBA00008303}.
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DR EMBL; DQ411561; ABE02678.1; -; Genomic_RNA.
DR MEROPS; N08.001; -.
DR GO; GO:0019028; C:viral capsid; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0044694; P:pore-mediated entry of viral genome into host cell; IEA:UniProtKB-KW.
DR GO; GO:0039657; P:suppression by virus of host gene expression; IEA:UniProtKB-KW.
DR GO; GO:0019062; P:virion attachment to host cell; IEA:UniProtKB-KW.
DR CDD; cd00205; rhv_like; 2.
DR Gene3D; 2.60.120.20; -; 2.
DR InterPro; IPR003138; Pico_P1A.
DR InterPro; IPR001676; Picornavirus_capsid.
DR InterPro; IPR033703; Rhv-like.
DR InterPro; IPR029053; Viral_coat.
DR Pfam; PF02226; Pico_P1A; 1.
DR Pfam; PF00073; Rhv; 2.
DR SUPFAM; SSF88633; Positive stranded ssRNA viruses; 2.
PE 3: Inferred from homology;
KW Capsid protein {ECO:0000256|ARBA:ARBA00022561};
KW Eukaryotic host gene expression shutoff by virus
KW {ECO:0000256|ARBA:ARBA00023247};
KW Eukaryotic host translation shutoff by virus
KW {ECO:0000256|ARBA:ARBA00022809};
KW Host gene expression shutoff by virus {ECO:0000256|ARBA:ARBA00022995};
KW Host-virus interaction {ECO:0000256|ARBA:ARBA00022581};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Myristate {ECO:0000256|ARBA:ARBA00022707};
KW Pore-mediated penetration of viral genome into host cell
KW {ECO:0000256|ARBA:ARBA00023255};
KW Viral attachment to host cell {ECO:0000256|ARBA:ARBA00022804};
KW Viral penetration into host cytoplasm {ECO:0000256|ARBA:ARBA00022595};
KW Virion {ECO:0000256|ARBA:ARBA00022561};
KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT DOMAIN 93..308
FT /note="Picornavirus capsid"
FT /evidence="ECO:0000259|Pfam:PF00073"
FT DOMAIN 370..529
FT /note="Picornavirus capsid"
FT /evidence="ECO:0000259|Pfam:PF00073"
FT NON_TER 613
FT /evidence="ECO:0000313|EMBL:ABE02678.1"
SQ SEQUENCE 613 AA; 67606 MW; 8A02562C0DFB79BD CRC64;
MGAQVSSQKV GAHENSNRAY GGSTINYTTI NYYRDSASNA ASKQDFSQDP SKFTEPIKDV
LIKTSPMLNS PNIEACGYSD RVLQLTLGNS TITTQEAANS VIAYGRWPEY LKDSEANPVD
QPTEPDVAAC RFYTLETVSW TKESRGWWWK LPDALRDMGL FGQNMYYHYL GRSGYTVHVQ
CNASKFHQGA LGVFAVPEMC LAGDSNTTTM HTSYQNANPG ERGGTFTGTF TPDVNQTSPA
RRFCPVDYLF GNGTLMGNAF VFPHQIINLR TNNCATLVLP YVNSLSIDSM VKHNNWGIAI
LPLAPLNFAN ESSPEIPITL TIAPMCCEFN GLRNITLPRL QGLPVMNTPG SNQYLTADNF
QSPCALPEFD VTPPIDIPGE VKNMMELAEI DTMIPFNLSA TKKNTMDMYR VQLSDKPHTE
DPILCLSLSP ASDPRLSHTM LGEILNYYTH WAGSLKFTFL FCGSMMATGK LLVSYAPPGA
DPPRKRKEAM LGTHVIWDVG LQSSCTMVVP WISNTTYRHT IDDSFTEGGY ISIFYQTKVV
VPLSTPREMD ILGFVSACND FSVRLLRDTT HIEQKALAQG LGQMLEGMID NTVRETVGAT
TSRDALPNTE ASG
//
