ID Q1QUQ3_CHRSD Unreviewed; 554 AA.
AC Q1QUQ3;
DT 16-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2006, sequence version 1.
DT 27-MAR-2024, entry version 118.
DE SubName: Full=Choline dehydrogenase {ECO:0000313|EMBL:ABE59805.1};
DE EC=1.1.99.1 {ECO:0000313|EMBL:ABE59805.1};
GN OrderedLocusNames=Csal_2458 {ECO:0000313|EMBL:ABE59805.1};
OS Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 /
OS NCIMB 13768 / 1H11).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Chromohalobacter.
OX NCBI_TaxID=290398 {ECO:0000313|EMBL:ABE59805.1, ECO:0000313|Proteomes:UP000000239};
RN [1] {ECO:0000313|EMBL:ABE59805.1, ECO:0000313|Proteomes:UP000000239}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11
RC {ECO:0000313|Proteomes:UP000000239};
RX PubMed=22675587; DOI=10.4056/sigs.2285059;
RA Copeland A., O'Connor K., Lucas S., Lapidus A., Berry K.W., Detter J.C.,
RA Del Rio T.G., Hammon N., Dalin E., Tice H., Pitluck S., Bruce D.,
RA Goodwin L., Han C., Tapia R., Saunders E., Schmutz J., Brettin T.,
RA Larimer F., Land M., Hauser L., Vargas C., Nieto J.J., Kyrpides N.C.,
RA Ivanova N., Goker M., Klenk H.P., Csonka L.N., Woyke T.;
RT "Complete genome sequence of the halophilic and highly halotolerant
RT Chromohalobacter salexigens type strain (1H11(T)).";
RL Stand. Genomic Sci. 5:379-388(2011).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790, ECO:0000256|RuleBase:RU003968}.
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DR EMBL; CP000285; ABE59805.1; -; Genomic_DNA.
DR RefSeq; WP_011507751.1; NC_007963.1.
DR AlphaFoldDB; Q1QUQ3; -.
DR STRING; 290398.Csal_2458; -.
DR KEGG; csa:Csal_2458; -.
DR eggNOG; COG2303; Bacteria.
DR HOGENOM; CLU_002865_7_1_6; -.
DR OrthoDB; 9785276at2; -.
DR Proteomes; UP000000239; Chromosome.
DR GO; GO:0008812; F:choline dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00623; GMC_OXRED_1; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU003968};
KW Oxidoreductase {ECO:0000313|EMBL:ABE59805.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000239}.
FT DOMAIN 84..107
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00623"
FT DOMAIN 256..270
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 94..97
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 554 AA; 60975 MW; C7E871D470CD5917 CRC64;
MTTHRDYDYI IVGAGSAGCV LADRLTADGE SRVLLLEAGP RDRSWTIDMP AAMGAAIDGP
RFNWHYWSGP EPYLDGRHIA TPRGRTLGGS SSINGMVYIR GHARDYDAWE DAGSPGWGYR
HVLPYFRRAE THELGADAYH GETGPLHVSA GRPEDPLAKA FLAAGEEAGY AASDDLNGYR
QEGFGRVDRT TRAGRRWSTA RGYLARAETR DNLTVVTHAL AQRVLIGETG AEGIEYRHAD
TLHRAHATRE VILAGGAINS PQLLMLSGIG PDDELTRWSI PRVHTLEGVG RRLSDHPDTV
VAYRCRRPVS HAPWTHAPRK WWLGMRWFLD RRGLAASNQF DAGAFIRSRA GVEHPDIQLT
FMSLAIAPGT TESLREHAFQ VHIDLMRPTS MGRLRLRSAD PAQAPEIVFN YLATERDRAD
MRAAVRRVRE LIEQPAFAAL RGEEISPGAD CQSDEALDAW ARATTETGYH AAGTCKMGPA
DDPEAVVDPE LRVHGISGLR VVDASIMPRV VSGNTNAPTV MIAEKASDMI LGHAPPAPSD
APFWLHDDWQ HQQR
//
