ID Q1RCN8_ECOUT Unreviewed; 642 AA.
AC Q1RCN8;
DT 16-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2006, sequence version 1.
DT 27-MAR-2024, entry version 117.
DE SubName: Full=Glycerol metabolism operon regulatory protein {ECO:0000313|EMBL:ABE06876.1};
GN OrderedLocusNames=UTI89_C1394 {ECO:0000313|EMBL:ABE06876.1};
OS Escherichia coli (strain UTI89 / UPEC).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=364106 {ECO:0000313|EMBL:ABE06876.1, ECO:0000313|Proteomes:UP000001952};
RN [1] {ECO:0000313|EMBL:ABE06876.1, ECO:0000313|Proteomes:UP000001952}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UTI89 / UPEC {ECO:0000313|Proteomes:UP000001952};
RX PubMed=16585510; DOI=10.1073/pnas.0600938103;
RA Chen S.L., Hung C.S., Xu J., Reigstad C.S., Magrini V., Sabo A.,
RA Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R., Fulton R.S.,
RA Latreille J.P., Spieth J., Hooton T.M., Mardis E.R., Hultgren S.J.,
RA Gordon J.I.;
RT "Identification of genes subject to positive selection in uropathogenic
RT strains of Escherichia coli: a comparative genomics approach.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2006).
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DR EMBL; CP000243; ABE06876.1; -; Genomic_DNA.
DR AlphaFoldDB; Q1RCN8; -.
DR KEGG; eci:UTI89_C1394; -.
DR HOGENOM; CLU_000445_8_12_6; -.
DR Proteomes; UP000001952; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0043170; P:macromolecule metabolic process; IEA:UniProt.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:UniProt.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR PANTHER; PTHR32071:SF121; PTS-DEPENDENT DIHYDROXYACETONE KINASE OPERON REGULATORY PROTEIN-RELATED; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 330..555
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
SQ SEQUENCE 642 AA; 70927 MW; 5C78AE5FF44839DA CRC64;
MRDMSGAFNN DGRGISPLIA TSWERCNKLM KRETWNVPHQ AQGVTFASIY RRKKAMLTLG
QAALEDAWEY MASRECALLI LDETACILSR NGDPQTLQQL STLGFNDGTY CAEGIIGTCA
LSLAAISGQA VKTMADQHFK QALWNWAFCA TPLFDSKGRL TGTIALACPV EQTTAADLPL
TLAIAREVGN LLLTDSLLAE TNRHLNQLNA LLESMDDGVI SWDEQGNLQF INAQAARVLR
LDATASQGRA ITELLTLPAV LQQAIKQSHP LKHVEATFES QHQFIDAVIT LKPIIETQGT
SFILLLHPVE QMRQLMTSQL GKVSHTFAHM PQDDPQTRRL IHFGRQAARS SFPVLLCGEE
GVGKALLSQA IHNESERAAG PYIAVNCELY GDAALAEEFI GGDRTDSENG RLSRLELAHG
GTLFLEKIEY LAVELQSALL QVIKQGVITR LDARRLIPID VKVIATTTAD LAMLVEQNRF
SRQLYYALHA FEITIPPLRM RRGSIPALVN NKLRSLEKRF STRLKIDDDA LARLVSCAWP
GNDFELYSVI ENLALSSDNG RIRVSDLPEH LFTEQATDDV SATRLSTSLS FAEVEKEAII
NAAQVTGGRI QEMSALLGIG RTTLWRKMKQ HGIDVSQFKR RG
//
