ID Q23CV6_TETTS Unreviewed; 515 AA.
AC Q23CV6;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 18-APR-2006, sequence version 1.
DT 24-JAN-2024, entry version 77.
DE SubName: Full=Flavin-binding monooxygenase-like protein {ECO:0000313|EMBL:EAR94354.1};
GN ORFNames=TTHERM_00052340 {ECO:0000313|EMBL:EAR94354.1};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR94354.1, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
CC -!- SIMILARITY: Belongs to the FMO family. {ECO:0000256|ARBA:ARBA00009183}.
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DR EMBL; GG662712; EAR94354.1; -; Genomic_DNA.
DR RefSeq; XP_001014930.1; XM_001014930.3.
DR AlphaFoldDB; Q23CV6; -.
DR STRING; 312017.Q23CV6; -.
DR EnsemblProtists; EAR94354; EAR94354; TTHERM_00052340.
DR GeneID; 7843941; -.
DR KEGG; tet:TTHERM_00052340; -.
DR eggNOG; KOG1399; Eukaryota.
DR HOGENOM; CLU_529478_0_0_1; -.
DR InParanoid; Q23CV6; -.
DR OMA; FMEWEHH; -.
DR OrthoDB; 2453855at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR000960; Flavin_mOase.
DR InterPro; IPR020946; Flavin_mOase-like.
DR PANTHER; PTHR23023; DIMETHYLANILINE MONOOXYGENASE; 1.
DR PANTHER; PTHR23023:SF266; FLAVIN-CONTAINING MONOOXYGENASE; 1.
DR Pfam; PF00743; FMO-like; 2.
DR PIRSF; PIRSF000332; FMO; 2.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033, ECO:0000313|EMBL:EAR94354.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168}.
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 515 AA; 59260 MW; 1FDFEA1BA07FA805 CRC64;
MIEEQLAEPA NPNQEQGAPQ APQSQQVEKK KILVIGAGPC GILATKHLSI NNDVICVDSK
EGLGGLWHYD KHDENNHPNL NQNAYYQNYG VLQSSLYEDM VSNFPKCLMT YKGFPPKKEY
NQFMTTAEFN DYLNCYTAHF DIQKCMKFNT FVVKVRLAAN MTEEELQKVG FNVTKRFVAS
LCPSESYKAD KSNISYIEVD SVVVCSGHDS VPNYPKIENR EVFEGDVIHM HNFRKHKLDQ
YKNTHVLIYG ANMSAQDLVQ FMITDKDKRA SKVTVLGNKQ LISQFEKTKA YKKEIDEGIL
EMRVGVIRNY LGKQSIILED ETVIDKIDNI IYATGYQYRY PFLEDTGDNL IETYNKESRC
NAFGPLYRRI FSIREPNLVF LGLIAGQLTI EAMYERQAIV AKRVLDGDVL LPSKEDMLRE
FKLEYDEIQK YSKDFKNFFK ISNREGVGSV QELNYIKMCQ EIAQIPIDEE FQKIAFEVCG
PIMDSYMAQG NYAFMKKHDF GSLYPENYSP NPSLF
//
