ID Q23EE7_TETTS Unreviewed; 413 AA.
AC Q23EE7;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 2.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Amidinotransferase {ECO:0000313|EMBL:EAR94910.2};
GN ORFNames=TTHERM_01029920 {ECO:0000313|EMBL:EAR94910.2};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR94910.2, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
CC -!- SIMILARITY: Belongs to the DDAH family.
CC {ECO:0000256|ARBA:ARBA00008532}.
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DR EMBL; GG662710; EAR94910.2; -; Genomic_DNA.
DR RefSeq; XP_001015155.2; XM_001015155.2.
DR AlphaFoldDB; Q23EE7; -.
DR STRING; 312017.Q23EE7; -.
DR EnsemblProtists; EAR94910; EAR94910; TTHERM_01029920.
DR GeneID; 7824835; -.
DR KEGG; tet:TTHERM_01029920; -.
DR eggNOG; ENOG502SCGJ; Eukaryota.
DR HOGENOM; CLU_701123_0_0_1; -.
DR InParanoid; Q23EE7; -.
DR OrthoDB; 2872132at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR InterPro; IPR033199; DDAH-like.
DR PANTHER; PTHR12737:SF9; DIMETHYLARGININASE; 1.
DR PANTHER; PTHR12737; DIMETHYLARGININE DIMETHYLAMINOHYDROLASE; 1.
DR SUPFAM; SSF55909; Pentein; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168}.
FT ACT_SITE 311
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-1"
FT ACT_SITE 405
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-1"
SQ SEQUENCE 413 AA; 47333 MW; B04594EDDE0F0569 CRC64;
MQRAYLYQIV TQFDNYLMIK KISKSKTKNS KHQQTSKQSI KLNQAKKKIF LKQIQMDSAT
QNQHQIEQSA KQIEGTFDKV KSSLNTCNQD DIHPIQNILS AELKSGTDGR GKKANISSDI
LSNIISGTQA ENQVESSTST SRKLTCNRQL FLCSPDFLQL KYVINPWMDL SAQFSVEKAK
QQWEELVNTY KRLVPESVHT VPPRENLTEL CFFGDSVFAI NKKAVFGRFA TNERFPETEY
VIEYLRSQGF QGERVPEGMH YEGSGETMVW NGKILVGYGK RNTKEIVSYL QTVYSDMEVI
GFQLIDPEFY HLDTAMFPIS ENLIAVYENA FSEEAKQQIK KLGCEIIYLT YKDAKEFACN
STVIGKHAIV HYEAENFINQ LKQRGFQVHT VDVSEFIKFG GGLKCLTFQH YLL
//
