ID Q23QC6_TETTS Unreviewed; 637 AA.
AC Q23QC6;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 18-APR-2006, sequence version 1.
DT 24-JAN-2024, entry version 87.
DE SubName: Full=PX-SNARE domain protein {ECO:0000313|EMBL:EAR98658.1};
GN ORFNames=TTHERM_00581600 {ECO:0000313|EMBL:EAR98658.1};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR98658.1, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
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DR EMBL; GG662649; EAR98658.1; -; Genomic_DNA.
DR RefSeq; XP_001018903.1; XM_001018903.1.
DR AlphaFoldDB; Q23QC6; -.
DR STRING; 312017.Q23QC6; -.
DR EnsemblProtists; EAR98658; EAR98658; TTHERM_00581600.
DR GeneID; 7842341; -.
DR KEGG; tet:TTHERM_00581600; -.
DR eggNOG; ENOG502R2GK; Eukaryota.
DR HOGENOM; CLU_429930_0_0_1; -.
DR InParanoid; Q23QC6; -.
DR OMA; CRAHEST; -.
DR OrthoDB; 179908at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06093; PX_domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR042234; WDFY1/WDFY2.
DR PANTHER; PTHR46189; LD41958P; 1.
DR PANTHER; PTHR46189:SF1; LD41958P; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 11..122
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REPEAT 429..470
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 513..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 513..547
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 557..571
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 572..587
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..637
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 637 AA; 74577 MW; 36A124B8A5ECD115 CRC64;
MDKKDNYTVD QFLQNFTLEL ITLDTKQNDK VYYTLEMELK DRRVKWRIEK RFSDFEALHL
DLSKTTIELP YLPPKSLFKL QQQDLQKRKS DLQKYLKSLV VRPDILQNEI FQEFLELNKY
GTVPKQVNYR QLGSISGFSM KVRDIHYEES QGIIFVLIGD NDLKTKVGGF LSSLLGTSKK
GDPCGRLICL RAKNQYTFDF NKLWHIDFYS HPQCMHFDPK LTMVAVGLYN GDIEIYRVKV
EKNYQSYEDY CIIKRHTSAI TAVHLDFQSA TVYSISRDKA FLVTNIANND SHYRIDEKIL
THPLTALCVD SINERVFVGD SVGSIYVYTT VEPIQIITSV FLEYENQINA IHITKQKNYI
LFGHATGLIR VFELKKKGSD RVLNPISAIT GPDNLHSLSF SLKDKEIYSN CTNSLLIIDS
AHNLPVISIN AHKDLITKIQ YVEERNIFVT ASKDFTVKFW KLRGSKDDKE SEFEQLYLAN
QNNKHQQKQV AELQAEIQKS SINPIEESRQ KFQEKLDKEK KEQEQRRLEE EAKKKKQQKL
YRQYDSDSDD LDSDDDDDKY NKNKQVQTKK EEVQTSQKSQ QQNKISKDQI KSEVKPQEKS
TSSNPKQQQQ KEQKREEEEE EEQEQEDDDD NIFGWDK
//
