ID Q247T2_TETTS Unreviewed; 410 AA.
AC Q247T2;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 2.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Ras family small GTPase {ECO:0000313|EMBL:EAS04018.2};
GN ORFNames=TTHERM_00994150 {ECO:0000313|EMBL:EAS04018.2};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAS04018.2, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
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DR EMBL; GG662458; EAS04018.2; -; Genomic_DNA.
DR RefSeq; XP_001024263.2; XM_001024263.2.
DR AlphaFoldDB; Q247T2; -.
DR STRING; 312017.Q247T2; -.
DR EnsemblProtists; EAS04018; EAS04018; TTHERM_00994150.
DR GeneID; 7831523; -.
DR KEGG; tet:TTHERM_00994150; -.
DR eggNOG; KOG0098; Eukaryota.
DR HOGENOM; CLU_041217_10_2_1; -.
DR InParanoid; Q247T2; -.
DR OrthoDB; 3487147at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd00154; Rab; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR47977; RAS-RELATED PROTEIN RAB; 1.
DR Pfam; PF00071; Ras; 2.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 2.
DR SMART; SM00173; RAS; 2.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51419; RAB; 2.
DR PROSITE; PS51421; RAS; 2.
DR PROSITE; PS51420; RHO; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009168}.
SQ SEQUENCE 410 AA; 48424 MW; EEC20D3C92F575CB CRC64;
MKNIFKLQIK CLTDIKIQIS SSRQEKKKEI NHKRFKILSS SKQMLRKEDY LFYIQIFGES
SIKFKLNQYI NFQSKFILFI KLQVKVVLFY KLHKITSKMN MIKRLHQNQQ LKQQNKIIKS
LNYASGIQQL INKQPGQKIL RCLVLHSYEK TAQGAILIYD ITNRENFLNI SGIIKQIRDS
EKSYVPLILV GNKFDLEQNR EVSYTEGENF AKEHDLFFFE VSAFTGYNIE VLFNKITELV
LKQVSNLIEE KKITVGKSCI VLQASENKFK DEHDKTIGVE FLNKIIQYDN KIFKLSIWDT
AGQSRFRSIV FCYFEKAQGV ILVYDITNRE SFLNISEFIQ KCRERTRSYV PLILVGNKFD
LEQNRQVSYT EGENFAKKHD LFFFEVSAYT GYNIDELFNK ITELVYENQK
//
