ID Q26C42_FLABB Unreviewed; 628 AA.
AC Q26C42;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 18-APR-2006, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=ATP-dependent dead/H DNA helicase {ECO:0000313|EMBL:EAS18923.1};
DE EC=3.6.1.- {ECO:0000313|EMBL:EAS18923.1};
GN ORFNames=BBFL7_00368 {ECO:0000313|EMBL:EAS18923.1};
OS Flavobacteria bacterium (strain BBFL7).
OC Bacteria; Bacteroidota; Flavobacteriia.
OX NCBI_TaxID=156586 {ECO:0000313|EMBL:EAS18923.1, ECO:0000313|Proteomes:UP000002172};
RN [1] {ECO:0000313|EMBL:EAS18923.1, ECO:0000313|Proteomes:UP000002172}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BBFL7 {ECO:0000313|EMBL:EAS18923.1,
RC ECO:0000313|Proteomes:UP000002172};
RA Azam F., Beardsley C., Gaasterland T., Malfatti F., Mayali X., Podell S.,
RA Samo T., Smriga S., Ferriera S., Johnson J., Kravitz S., Halpern A.,
RA Remington K., Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAS18923.1}.
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DR EMBL; AAPD01000007; EAS18923.1; -; Genomic_DNA.
DR AlphaFoldDB; Q26C42; -.
DR STRING; 156586.BBFL7_00368; -.
DR HOGENOM; CLU_001103_9_7_10; -.
DR Proteomes; UP000002172; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EAS18923.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EAS18923.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002172}.
FT DOMAIN 26..194
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 215..372
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 628 AA; 71685 MW; A369D8C20404ACFF CRC64;
MNPEAKSILK NTFGFDDFRP QQEEIITAVI DGNDIMALLP TGGGKSLCYQ IPGLVRNGIC
IVISPLVALI KDQVNTLKQK GIKATGITGG ISYKELDDIL DNCIYGQYQF LYLSPERLQQ
SLVQERISKM RISLIAVDEA HCISQWGHDF RPAYRDISLL RSIHKEVPVI AVTATATTSV
QKDIIENLQL ENVKVFKNSY LRPNISYQIT NTTDKSNSYI NFYRNHGGSS VTYVRSRKNA
IEYSRLLTSH GISSGFFHGG LPNKIKVDTA QRWMKNQTQV MVATNAFGMG IDKPDVRTVV
HLQLPDSIES YYQETGRAGR DGKNSIAQFF YNINDINHAQ NQFIKSLPSV ENIKFVYRKL
NNYLRIAMNE GEHTTHQLSF SDFARTYSIN GMMCYNALLT LDRFSVISLS QSYHRRSNIR
FRESGKNIIN FLGNHKEMNA IVQAILRTYG SSTYQNLEIN TSIIALRSNT TEQKVIETLQ
KLEEQEYIEA NIIDADTQIN FLVPRDDDRT INRFSKELSK QNEIKKQKLE QIFYLISQNK
QCINMLILRY FGEKSNPCGN CSVCRDQKST VLLLDRIKDV LIKRDLNSNE IASLLPEADK
NNIVETLKLL LEQGKVSIHQ NHKYHWNG
//
