ID   Q27JJ5_HCMV             Unreviewed;       172 AA.
AC   Q27JJ5;
DT   04-APR-2006, integrated into UniProtKB/TrEMBL.
DT   04-APR-2006, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=UL144 protein {ECO:0000313|EMBL:ABD48749.1};
OS   Human cytomegalovirus (HHV-5) (Human herpesvirus 5).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Orthoherpesviridae; Betaherpesvirinae; Cytomegalovirus;
OC   Cytomegalovirus humanbeta5.
OX   NCBI_TaxID=10359 {ECO:0000313|EMBL:ABD48749.1};
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1] {ECO:0000313|EMBL:ABD48749.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=16896551; DOI=10.1007/s00705-006-0826-8;
RA   Mao Z.Q., He R., Sun M., Qi Y., Huang Y.J., Ruan Q.;
RT   "The relationship between polymorphisms of HCMV UL144 ORF and clinical
RT   manifestations in 73 strains with congenital and/or perinatal HCMV
RT   infection.";
RL   Arch. Virol. 152:115-124(2007).
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DR   EMBL; DQ393834; ABD48749.1; -; Genomic_DNA.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 1.
DR   InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR   PANTHER; PTHR46838; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14; 1.
DR   PANTHER; PTHR46838:SF1; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14; 1.
DR   Pfam; PF00020; TNFR_c6; 1.
DR   SMART; SM00208; TNFR; 2.
DR   SUPFAM; SSF57586; TNF receptor-like; 1.
DR   PROSITE; PS00652; TNFR_NGFR_1; 1.
DR   PROSITE; PS50050; TNFR_NGFR_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        130..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          58..95
FT                   /note="TNFR-Cys"
FT                   /evidence="ECO:0000259|PROSITE:PS50050"
SQ   SEQUENCE   172 AA;  18883 MW;  6AEBB5F2EB062BE7 CRC64;
     MKPLVMLICF GVFLLQLGGS KMCKPDEVKL GNQCCPPCGS GQKVTKVCTE NSGITCTLCP
     NGTYLTGLYN CTNCTQCNDT QITVRNCTST NNTICASKNY TSLSVPGVQH HKQRQNHTAH
     VTVKQGKSGL AWLSLFIFLV GIILLILYLI AAYRSERCQQ CCSIGKIFYR TL
//