ID Q28347_CERTR Unreviewed; 289 AA.
AC Q28347;
DT 01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1996, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=B7 protein {ECO:0000313|EMBL:AAA86700.1};
DE Flags: Fragment;
GN Name=B7 {ECO:0000313|EMBL:AAA86700.1};
OS Cercocebus torquatus (Red-capped mangabey) (Cercocebus torquatus subsp.
OS torquatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9530 {ECO:0000313|EMBL:AAA86700.1};
RN [1] {ECO:0000313|EMBL:AAA86700.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:AAA86700.1};
RX PubMed=7561102;
RA Villinger F., Brar S.S., Mayne A., Chikkala N., Ansari A.A.;
RT "Comparative sequence analysis of cytokine genes from human and nonhuman
RT primates.";
RL J. Immunol. 155:3946-3954(1995).
RN [2] {ECO:0000313|EMBL:AAA86700.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:AAA86700.1};
RA Villinger F.J.;
RL Submitted (JAN-1995) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; U19833; AAA86700.1; -; mRNA.
DR PIR; G00031; G00031.
DR AlphaFoldDB; Q28347; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015026; F:coreceptor activity; IEA:InterPro.
DR GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; ISS:UniProtKB.
DR GO; GO:0031295; P:T cell costimulation; IEA:InterPro.
DR CDD; cd16083; IgC1_CD80; 1.
DR CDD; cd16086; IgV_CD80; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR037676; CD80_IgC.
DR InterPro; IPR042711; CD80_IgV.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR25466; T-LYMPHOCYTE ACTIVATION ANTIGEN; 1.
DR PANTHER; PTHR25466:SF4; T-LYMPHOCYTE ACTIVATION ANTIGEN CD80; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07686; V-set; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..289
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004203563"
FT TRANSMEM 247..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 145..230
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT NON_TER 289
FT /evidence="ECO:0000313|EMBL:AAA86700.1"
SQ SEQUENCE 289 AA; 33030 MW; 5ED6A3F6A3C59297 CRC64;
MGHTRRQGIS SSKCPYLKFF QLLVLACLSH FCSGVIHVTK EVKEVATLSC GHNVSVEELA
QTRIYCQKEK KMVLTMISGD MNIWPEYKNR TIFDITNNLS IVILALRPSD EGTYECVVLK
YEKDAFKREH LAEVMLSVKA DFPTPSITDF EIPPSNIRRI ICSTSGGFPE PHLSWLENGG
ELNAIDTTVS QDPETELYTV SSKLDFNMTT NHSFVCLIKY GHLRVNQTFN WNTPKQEHFP
DNLLPSWAIT LISVNGIFVI CCLTYCFAPR CRERRRNETL RRESVRPVL
//
