ID Q28G89_XENTR Unreviewed; 129 AA.
AC Q28G89; F7C4E8;
DT 04-APR-2006, integrated into UniProtKB/TrEMBL.
DT 04-APR-2006, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Protein phosphatase 1 regulatory inhibitor subunit 14B {ECO:0000313|Ensembl:ENSXETP00000015645};
DE SubName: Full=Protein phosphatase 1 regulatory subunit 14B {ECO:0000313|RefSeq:NP_001016307.1};
DE SubName: Full=Protein phosphatase 1, regulatory (Inhibitor) subunit 14B {ECO:0000313|EMBL:CAJ83896.1};
GN Name=ppp1r14b {ECO:0000313|EMBL:CAJ83896.1,
GN ECO:0000313|Ensembl:ENSXETP00000015645,
GN ECO:0000313|RefSeq:NP_001016307.1,
GN ECO:0000313|Xenbase:XB-GENE-485314};
GN Synonyms=phi-1 {ECO:0000313|RefSeq:NP_001016307.1}, plcb3n
GN {ECO:0000313|RefSeq:NP_001016307.1}, png
GN {ECO:0000313|RefSeq:NP_001016307.1}, som172
GN {ECO:0000313|RefSeq:NP_001016307.1};
GN ORFNames=TGas100n20.1-001 {ECO:0000313|EMBL:CAJ83896.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:CAJ83896.1};
RN [1] {ECO:0000313|EMBL:CAJ83896.1}
RP NUCLEOTIDE SEQUENCE.
RA Amaya E., Ashurst J.L., Bonfield J.K., Croning M.D.R., Chen C-K.,
RA Davies R.M., Francis M.D., Garrett N., Gilchrist M.J., Grafham D.V.,
RA McLaren S.R., Papalopulu N., Rogers J., Smith J.C., Taylor R.G., Voigt J.,
RA Zorn A.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSXETP00000015645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000015645};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [3] {ECO:0000313|Ensembl:ENSXETP00000015645}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [4] {ECO:0000313|RefSeq:NP_001016307.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PP1 inhibitor family.
CC {ECO:0000256|ARBA:ARBA00005483}.
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DR EMBL; CR761497; CAJ83896.1; -; mRNA.
DR RefSeq; NP_001016307.1; NM_001016307.2.
DR Ensembl; ENSXETT00000015645; ENSXETP00000015645; ENSXETG00000007199.
DR GeneID; 549061; -.
DR KEGG; xtr:549061; -.
DR AGR; Xenbase:XB-GENE-485314; -.
DR CTD; 26472; -.
DR Xenbase; XB-GENE-485314; ppp1r14b.
DR eggNOG; KOG0824; Eukaryota.
DR HOGENOM; CLU_114155_1_0_1; -.
DR OMA; GAGEASX; -.
DR OrthoDB; 5321897at2759; -.
DR TreeFam; TF105546; -.
DR Proteomes; UP000008143; Chromosome 4.
DR Bgee; ENSXETG00000007199; Expressed in heart and 25 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR GO; GO:0042325; P:regulation of phosphorylation; IEA:InterPro.
DR Gene3D; 1.10.150.220; CPI-17; 1.
DR InterPro; IPR008025; CPI-17.
DR InterPro; IPR036658; CPI-17_sf.
DR PANTHER; PTHR16188; PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C; 1.
DR PANTHER; PTHR16188:SF5; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14B; 1.
DR Pfam; PF05361; PP1_inhibitor; 1.
DR SUPFAM; SSF81790; Myosin phosphatase inhibitor 17kDa protein, CPI-17; 1.
PE 2: Evidence at transcript level;
KW Protein phosphatase inhibitor {ECO:0000256|ARBA:ARBA00023272};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143}.
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 129 AA; 14912 MW; 6A71C4246E6579ED CRC64;
MAALSSPGSS PHPTSPRVYF QAPGETAEEP ERRHQGKVTV KYDRKELRKR LRLEEWILEQ
LVVLYDCQEE EIPELEIDVD ELLDMETDAQ RGERVKELLV DCYKPTEAFI SGLLEKIQGM
QKLSTPQKK
//
