ID   Q2H4S1_CHAGB            Unreviewed;       532 AA.
AC   Q2H4S1;
DT   21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 69.
DE   RecName: Full=FAD-binding PCMH-type domain-containing protein {ECO:0000259|PROSITE:PS51387};
GN   ORFNames=CHGG_06344 {ECO:0000313|EMBL:EAQ89725.1};
OS   Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS   NRRL 1970) (Soil fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX   NCBI_TaxID=306901 {ECO:0000313|EMBL:EAQ89725.1, ECO:0000313|Proteomes:UP000001056};
RN   [1] {ECO:0000313|Proteomes:UP000001056}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970
RC   {ECO:0000313|Proteomes:UP000001056};
RX   PubMed=25720678; DOI=10.1128/genomeA.00021-15;
RA   Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT   "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL   Genome Announc. 3:E0002115-E0002115(2015).
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DR   EMBL; CH408031; EAQ89725.1; -; Genomic_DNA.
DR   RefSeq; XP_001222439.1; XM_001222438.1.
DR   AlphaFoldDB; Q2H4S1; -.
DR   STRING; 306901.Q2H4S1; -.
DR   GeneID; 4391503; -.
DR   VEuPathDB; FungiDB:CHGG_06344; -.
DR   eggNOG; KOG4730; Eukaryota.
DR   HOGENOM; CLU_530170_0_0_1; -.
DR   InParanoid; Q2H4S1; -.
DR   OMA; KFGRPYF; -.
DR   OrthoDB; 2229906at2759; -.
DR   Proteomes; UP000001056; Unassembled WGS sequence.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0016899; F:oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor; IEA:InterPro.
DR   Gene3D; 3.30.465.10; -; 1.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR010031; FAD_lactone_oxidase-like.
DR   InterPro; IPR006094; Oxid_FAD_bind_N.
DR   PANTHER; PTHR43762; L-GULONOLACTONE OXIDASE; 1.
DR   PANTHER; PTHR43762:SF1; L-GULONOLACTONE OXIDASE; 1.
DR   Pfam; PF01565; FAD_binding_4; 1.
DR   SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001056};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..532
FT                   /note="FAD-binding PCMH-type domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004209275"
FT   DOMAIN          32..218
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51387"
FT   REGION          474..523
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   532 AA;  59181 MW;  958CBCE6E45F94BE CRC64;
     MRSLPHLLAA LLTTTGAAAF EYNTFDGPGF PSCYNVSRVH NATSVADMAA VVKEVAAAAS
     SSSSSSAVGR VRAAGKGHMW YDTQCSDAWT VVVRTEQVNA ISEFALPAGA DRGSVWVEAG
     TTFFQLAEYL HARGASVGYT LTNWNISFGG SVAMGAHRSS IREESMVAAG VLAMDIIDGS
     GEVRRVVRDE GDDEWLAAST SLGLLGIIAR IQLQVYARER IGGVADKFRL DEKDVLDGDI
     YGMIAPYATA NLWWWPYKRK FHHRYYDPVP SNSTPQEGFQ NTFSVTELEA IAARTLLDSG
     KYLPTSNMLA EEIFFGLWEK PNFREKTTNE EIKEWPVYGW NYDVLIGGLY PDQKAEWEYG
     LAGYTMELAF PMPLANKMLK RVRQLFDDEL KKGIVMTSTY RSGINIKFGK AYFDFLGQVT
     YNTTDGADWT KGAIMFDFPS FRPTIGDHKR FNEQFCKGIW YKASGTTVEL TVTQRPQSSQ
     HAHRRVPRAA RTGTKNTREV FTRSVKNLDP KSPAHLHDAS VSRPYADLFS PP
//