ID Q2K7V6_RHIEC Unreviewed; 254 AA.
AC Q2K7V6;
DT 07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 07-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase protein (4-hydroxyphenylacetate catabolism protein) {ECO:0000313|EMBL:ABC91080.1};
GN Name=hpaI {ECO:0000313|EMBL:ABC91080.1};
GN OrderedLocusNames=RHE_CH02300 {ECO:0000313|EMBL:ABC91080.1};
OS Rhizobium etli (strain CFN 42 / ATCC 51251).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX NCBI_TaxID=347834 {ECO:0000313|EMBL:ABC91080.1, ECO:0000313|Proteomes:UP000001936};
RN [1] {ECO:0000313|EMBL:ABC91080.1, ECO:0000313|Proteomes:UP000001936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFN 42 / ATCC 51251 {ECO:0000313|Proteomes:UP000001936};
RX PubMed=16505379; DOI=10.1073/pnas.0508502103;
RA Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I.,
RA Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A.,
RA Jimenez-Jacinto V., Collado-Vides J., Davila G.;
RT "The partitioned Rhizobium etli genome: genetic and metabolic redundancy in
RT seven interacting replicons.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006).
CC -!- SIMILARITY: Belongs to the HpcH/HpaI aldolase family.
CC {ECO:0000256|ARBA:ARBA00005568}.
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DR EMBL; CP000133; ABC91080.1; -; Genomic_DNA.
DR RefSeq; WP_011425560.1; NC_007761.1.
DR AlphaFoldDB; Q2K7V6; -.
DR KEGG; ret:RHE_CH02300; -.
DR eggNOG; COG3836; Bacteria.
DR HOGENOM; CLU_059964_1_0_5; -.
DR OrthoDB; 9802624at2; -.
DR Proteomes; UP000001936; Chromosome.
DR GO; GO:0018802; F:2,4-dihydroxyhept-2-ene-1,7-dioate aldolase activity; IEA:InterPro.
DR GO; GO:0010124; P:phenylacetate catabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR InterPro; IPR005000; Aldolase/citrate-lyase_domain.
DR InterPro; IPR012689; HpaI.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR NCBIfam; TIGR02311; HpaI; 1.
DR PANTHER; PTHR30502; 2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE; 1.
DR PANTHER; PTHR30502:SF0; PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN; 1.
DR Pfam; PF03328; HpcH_HpaI; 1.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
PE 3: Inferred from homology;
KW Aromatic hydrocarbons catabolism {ECO:0000256|ARBA:ARBA00022797};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Reference proteome {ECO:0000313|Proteomes:UP000001936}.
FT DOMAIN 18..242
FT /note="HpcH/HpaI aldolase/citrate lyase"
FT /evidence="ECO:0000259|Pfam:PF03328"
SQ SEQUENCE 254 AA; 26976 MW; 36DBEBAE14425BE1 CRC64;
MELPVNHFKR KLRAGKSQIG LWCGLPGSYA AEIVAPAGFD WVLFDTEHSP SDVLTVLPQL
QAVAPYDVSP VVRPASNDPV LIKRFLDIGV QTLLVPYVQN EEEAKAAVAA IRYPPHGVRG
VSALTRATRF GRVPNYARIA EQEICLLLQI ETREALGRLE AIATVEGVDG VFIGPADLAA
SFGHPGQPGH PEVVAAIEDA IGRLKILGKP AGILTPDETF AARCISLGTS FTAVGVDIAL
LARGSEALAA RFAT
//
