ID Q2LUK3_SYNAS Unreviewed; 289 AA.
AC Q2LUK3;
DT 21-FEB-2006, integrated into UniProtKB/TrEMBL.
DT 21-FEB-2006, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE RecName: Full=RNA polymerase sigma factor {ECO:0000256|RuleBase:RU362124};
GN ORFNames=SYN_00639 {ECO:0000313|EMBL:ABC77759.1};
OS Syntrophus aciditrophicus (strain SB).
OC Bacteria; Thermodesulfobacteriota; Syntrophia; Syntrophales; Syntrophaceae;
OC Syntrophus.
OX NCBI_TaxID=56780 {ECO:0000313|EMBL:ABC77759.1, ECO:0000313|Proteomes:UP000001933};
RN [1] {ECO:0000313|EMBL:ABC77759.1, ECO:0000313|Proteomes:UP000001933}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB {ECO:0000313|EMBL:ABC77759.1,
RC ECO:0000313|Proteomes:UP000001933};
RX PubMed=17442750; DOI=10.1073/pnas.0610456104;
RA McInerney M.J., Rohlin L., Mouttaki H., Kim U., Krupp R.S.,
RA Rios-Hernandez L., Sieber J., Struchtemeyer C.G., Bhattacharyya A.,
RA Campbell J.W., Gunsalus R.P.;
RT "The genome of Syntrophus aciditrophicus: life at the thermodynamic limit
RT of microbial growth.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:7600-7605(2007).
CC -!- FUNCTION: Sigma factors are initiation factors that promote the
CC attachment of RNA polymerase to specific initiation sites and are then
CC released. {ECO:0000256|RuleBase:RU362124}.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family.
CC {ECO:0000256|RuleBase:RU362124}.
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DR EMBL; CP000252; ABC77759.1; -; Genomic_DNA.
DR RefSeq; WP_011417781.1; NC_007759.1.
DR AlphaFoldDB; Q2LUK3; -.
DR STRING; 56780.SYN_00639; -.
DR KEGG; sat:SYN_00639; -.
DR eggNOG; COG0568; Bacteria.
DR HOGENOM; CLU_014793_3_5_7; -.
DR InParanoid; Q2LUK3; -.
DR OrthoDB; 9809557at2; -.
DR Proteomes; UP000001933; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR CDD; cd06171; Sigma70_r4; 1.
DR Gene3D; 1.10.601.10; RNA Polymerase Primary Sigma Factor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR000943; RNA_pol_sigma70.
DR InterPro; IPR009042; RNA_pol_sigma70_r1_2.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR007624; RNA_pol_sigma70_r3.
DR InterPro; IPR007630; RNA_pol_sigma70_r4.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR012759; RNA_pol_sigma_RpoH_proteobac.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02392; rpoH_proteo; 1.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR30376:SF3; RNA POLYMERASE SIGMA FACTOR RPOH; 1.
DR PANTHER; PTHR30376; SIGMA FACTOR RPOH HEAT SHOCK RELATED; 1.
DR Pfam; PF00140; Sigma70_r1_2; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF04539; Sigma70_r3; 1.
DR Pfam; PF04545; Sigma70_r4; 1.
DR PIRSF; PIRSF000770; RNA_pol_sigma-SigE/K; 1.
DR PRINTS; PR00046; SIGMA70FCT.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 2.
DR PROSITE; PS00715; SIGMA70_1; 1.
DR PROSITE; PS00716; SIGMA70_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU362124};
KW Reference proteome {ECO:0000313|Proteomes:UP000001933};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082,
KW ECO:0000256|RuleBase:RU362124};
KW Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU362124};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU362124}.
FT DOMAIN 71..84
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00715"
FT DOMAIN 244..270
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00716"
SQ SEQUENCE 289 AA; 33284 MW; 995A6FE38D7A85CE CRC64;
MKLPAIAGTL EVYIAEINRF PILTAEEEFR YAIEWKKNQN MEAAEKLVVS NLRFVVKIAH
EYRNYGVKLA DLIQEGNIGL MHAVKKFDPY KGYRLISYAV WWIRAYIQNY IIKTWSLVKI
GTTQAQRKLF FKLNKTKKDI QALSLKNPEF SEIAESLGVR EGEVEEMDVR MSNRDLSLDM
AIGDDGGSSH MDFLTYAGED QETALIRKEE AELVRKNITG ALAVLNEKEM YIIRNRVMAD
DPKTLQEIGD IYNITRERAR QIEKQALKKL RLALPYLGEE QKLLEAGSN
//
