ID Q2MEX4_STRHI Unreviewed; 469 AA.
AC Q2MEX4;
DT 21-FEB-2006, integrated into UniProtKB/TrEMBL.
DT 21-FEB-2006, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=2-deoxystreptamine N-acetyl-D-glucosaminyltransferase / 2-deoxystreptamine glucosyltransferase {ECO:0000313|EMBL:SHG39036.1};
DE SubName: Full=Putative glycosyltransferase {ECO:0000313|EMBL:CAI47650.1};
GN Name=aprM {ECO:0000313|EMBL:CAI47650.1};
GN ORFNames=SAMN05444320_108254 {ECO:0000313|EMBL:SHG39036.1},
GN ShinN01.15c {ECO:0000313|EMBL:CAI47650.1};
OS Streptoalloteichus hindustanus.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Streptoalloteichus.
OX NCBI_TaxID=2017 {ECO:0000313|EMBL:CAI47650.1};
RN [1] {ECO:0000313|EMBL:CAI47650.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Type strain:DSM 44523 {ECO:0000313|EMBL:CAI47650.1};
RA Aboshanab K.M., Schmidt-Beissner H., Wehmeier U.F., Welzel K., Vente A.,
RA Piepersberg W.;
RT "Comparison of the "mixed" gene clusters for the biosynthesis of the
RT aminoglycoside antibiotics apramycin (Streptoalloteichus hindustanus DSM
RT 44523 and Streptomyces tenebrarius DSM 40477)and hygromycin B (Streptomyces
RT hygroscopicus subsp. hygroscopicus DSM 40578), which contain genes related
RT to both the biosynthesis of other aminoglycosides and cell-wall sugars.";
RL Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:SHG39036.1, ECO:0000313|Proteomes:UP000184501}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44523 {ECO:0000313|EMBL:SHG39036.1,
RC ECO:0000313|Proteomes:UP000184501};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AJ875019; CAI47650.1; -; Genomic_DNA.
DR EMBL; FQVN01000008; SHG39036.1; -; Genomic_DNA.
DR AlphaFoldDB; Q2MEX4; -.
DR STRING; 2017.SAMN05444320_108254; -.
DR CAZy; GT4; Glycosyltransferase Family 4.
DR OrthoDB; 9771846at2; -.
DR Proteomes; UP000184501; Unassembled WGS sequence.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:1901137; P:carbohydrate derivative biosynthetic process; IEA:UniProt.
DR CDD; cd03819; GT4_WavL-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR028098; Glyco_trans_4-like_N.
DR PANTHER; PTHR45947; SULFOQUINOVOSYL TRANSFERASE SQD2; 1.
DR PANTHER; PTHR45947:SF3; SULFOQUINOVOSYL TRANSFERASE SQD2; 1.
DR Pfam; PF13439; Glyco_transf_4; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Reference proteome {ECO:0000313|Proteomes:UP000184501};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CAI47650.1}.
FT DOMAIN 27..211
FT /note="Glycosyltransferase subfamily 4-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13439"
FT DOMAIN 227..385
FT /note="Glycosyl transferase family 1"
FT /evidence="ECO:0000259|Pfam:PF00534"
FT REGION 416..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 427..449
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 469 AA; 50041 MW; 129F09C4523B7155 CRC64;
MRLRVLRLTP FFHHDCVDRW PAEFDAVGGM QVQILRLSRQ LARRGVRQEV LTVGFPGLPR
VREDSPGLVV RITRAPMPRL RSELTGLVGL NLAWFLGAMA ECARRRRSRR PDLIQVHADG
QLWALLAGPI ASALLRRPYS LVLHCSRLGV YQPMSRYDQW QHRFVAAVER WALRRADGVC
ALTARTADVV RAALRPHAVR VDVVPDSVDP EPPVDAGVPV AERLRAAGLP ADAKVVGYVG
RVAHEKGWAH FVELAARLAA DPPAEPVVFL VVGDGPQRPR MEERVAAAGL SDRFVFTGFL
PNHEVPLTMS GIDVLVMPSV HEELGGSAIE AMVLGVPVVA YGVGGLRDTV GTVAPELLVP
PQDVPALVRA VRDVLARGAE HRARVRAGRP WLEENFGDGV GVDRTVAHYR RVLAGRGGGG
DLGPGVPGPG VPNPGALNPG VPGPGGAAPA DPPDGGASAA GQRPPGSGP
//
