ID   Q2RG56_MOOTA            Unreviewed;       249 AA.
AC   Q2RG56;
DT   24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT   24-JAN-2006, sequence version 1.
DT   27-MAR-2024, entry version 80.
DE   SubName: Full=N-acetylmuramoyl-L-alanine amidase {ECO:0000313|EMBL:ABC20583.1};
DE            EC=3.5.1.28 {ECO:0000313|EMBL:ABC20583.1};
GN   OrderedLocusNames=Moth_2296 {ECO:0000313|EMBL:ABC20583.1};
OS   Moorella thermoacetica (strain ATCC 39073 / JCM 9320).
OC   Bacteria; Bacillota; Clostridia; Moorellales; Moorellaceae; Moorella.
OX   NCBI_TaxID=264732 {ECO:0000313|EMBL:ABC20583.1};
RN   [1] {ECO:0000313|EMBL:ABC20583.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 39073 {ECO:0000313|EMBL:ABC20583.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chertkov O., Saunders E.H., Brettin T.,
RA   Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Anderson I., Richardson P., Ragsdale S.;
RT   "Complete sequence of Moorella thermoacetica ATCC 39073.";
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000232; ABC20583.1; -; Genomic_DNA.
DR   RefSeq; YP_431126.1; NC_007644.1.
DR   AlphaFoldDB; Q2RG56; -.
DR   STRING; 264732.Moth_2296; -.
DR   EnsemblBacteria; ABC20583; ABC20583; Moth_2296.
DR   KEGG; mta:Moth_2296; -.
DR   PATRIC; fig|264732.11.peg.2501; -.
DR   eggNOG; COG0860; Bacteria.
DR   HOGENOM; CLU_014322_7_0_9; -.
DR   OrthoDB; 9772024at2; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
DR   CDD; cd02696; MurNAc-LAA; 1.
DR   Gene3D; 3.40.630.40; Zn-dependent exopeptidases; 1.
DR   InterPro; IPR002508; MurNAc-LAA_cat.
DR   PANTHER; PTHR30404; N-ACETYLMURAMOYL-L-ALANINE AMIDASE; 1.
DR   PANTHER; PTHR30404:SF0; N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIC; 1.
DR   Pfam; PF01520; Amidase_3; 1.
DR   SMART; SM00646; Ami_3; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ABC20583.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          124..233
FT                   /note="MurNAc-LAA"
FT                   /evidence="ECO:0000259|SMART:SM00646"
SQ   SEQUENCE   249 AA;  26603 MW;  DFA936D271D90BF5 CRC64;
     MGGGGLMARV VFVPRRRVRG LLIIALAVLG AFWVRIWYQG VKEEQAIQAL SWAVANQVVV
     VDPGHGGIDA GAMGPGGTPE HRVNLAISKD LAGFLKAGGA KVILTRQDDN VPLGESGDDL
     VERVRLAGKV GADLFISVHC NAFDSRERGA QLFYDPKSAE GKKLAESIQA EIKRLLANTD
     RVPLSIDAFV LRTQKIPAVI VEVGFISNPE EEKLLADPHY QRRMAFAIYA GIVNYLAGKG
     TPAGGKPAG
//