ID Q2RX02_RHORT Unreviewed; 720 AA.
AC Q2RX02;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN OrderedLocusNames=Rru_A0539 {ECO:0000313|EMBL:ABC21343.1};
OS Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 /
OS NCIMB 8255 / S1).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Rhodospirillaceae; Rhodospirillum.
OX NCBI_TaxID=269796 {ECO:0000313|EMBL:ABC21343.1, ECO:0000313|Proteomes:UP000001929};
RN [1] {ECO:0000313|EMBL:ABC21343.1, ECO:0000313|Proteomes:UP000001929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1
RC {ECO:0000313|Proteomes:UP000001929};
RX PubMed=21886856; DOI=10.4056/sigs.1804360;
RA Munk A.C., Copeland A., Lucas S., Lapidus A., Del Rio T.G., Barry K.,
RA Detter J.C., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D.,
RA Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Kyrpides N.C.,
RA Mavromatis K., Richardson P., Rohde M., Goker M., Klenk H.P., Zhang Y.,
RA Roberts G.P., Reslewic S., Schwartz D.C.;
RT "Complete genome sequence of Rhodospirillum rubrum type strain (S1).";
RL Stand. Genomic Sci. 4:293-302(2011).
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU364093}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000230; ABC21343.1; -; Genomic_DNA.
DR RefSeq; YP_425630.1; NC_007643.1.
DR AlphaFoldDB; Q2RX02; -.
DR STRING; 269796.Rru_A0539; -.
DR EnsemblBacteria; ABC21343; ABC21343; Rru_A0539.
DR KEGG; rru:Rru_A0539; -.
DR PATRIC; fig|269796.9.peg.593; -.
DR eggNOG; COG1298; Bacteria.
DR HOGENOM; CLU_015346_3_0_5; -.
DR PhylomeDB; Q2RX02; -.
DR Proteomes; UP000001929; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:ABC21343.1};
KW Cilium {ECO:0000313|EMBL:ABC21343.1};
KW Flagellum {ECO:0000313|EMBL:ABC21343.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000001929};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 65..88
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 140..163
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 232..253
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 273..291
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 720 AA; 78312 MW; 782B5A04BAF9FA75 CRC64;
MAEDLNQGRL TPLPVNGPGT PDGPPPFAFG AWARRMRELV VTGEFALPFG LIAILVVLIL
PMPTWLLDIM LAMSLTLSVL ILMTVVFIRK ALEFSTFPMV LLITTMLRLA LNLASTRLIL
AQGHEGTAAA GHVIEAFGGF IMGGNFVIGV IVFSILVLVN FMVITKGATR IAEVTARFTL
DAMPGKQMAI DADLSSGLID ETEARRRREE MQKESDFFGA MDGASKFVRG DAIAGIIITF
INVIGGMIIG IAQNDLTFSE AANTYTALTV GDGLVSQIPA LIISVAAGVM VSKGGLTTTA
ETALIGQFTA YPKALGMSAF LAGALALVPG TPALPFLLLA GLTGGAAWWL NRKASNIKRD
EAEHAQELAT QEIPVAEEPI STALKIDLVR LELGYGLLSL INTAHNQRLT DQIKALRRAL
ATDMGFVMPP VRIQDNMQLA ANTYRIYIKE VEAGHGDLRP TMLLVMDPRG DEITLAGEKT
HEPTFGLPAV WVDLSNREEA MFRGYTVVDP PTVITTHITE VVKDHMAELL SYAETQKLLD
DLDKEQQKLI ADMIPTQIST SGVQRVLQNL LAERVSIRDL PTILEGVAEA CGATRNIMMI
TEHVRTRIAR QLSDANVNED GIVPLVTLSP QWETAFAEAL IGQGEDRQLS MAPSKLQEFI
VGVRQTFERF AMQGESPVLL TSPMIRPYVR SIIERFRPMT VVMSQNEIHP KAKIKTLGQI
//
