ID   Q2RYX4_SALRD            Unreviewed;       939 AA.
AC   Q2RYX4;
DT   24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT   24-JAN-2006, sequence version 1.
DT   27-MAR-2024, entry version 90.
DE   SubName: Full=X-Pro dipeptidyl-peptidase {ECO:0000313|EMBL:ABC44609.1};
GN   OrderedLocusNames=SRU_2765 {ECO:0000313|EMBL:ABC44609.1};
OS   Salinibacter ruber (strain DSM 13855 / M31).
OC   Bacteria; Rhodothermota; Rhodothermia; Rhodothermales; Salinibacteraceae;
OC   Salinibacter.
OX   NCBI_TaxID=309807 {ECO:0000313|EMBL:ABC44609.1, ECO:0000313|Proteomes:UP000008674};
RN   [1] {ECO:0000313|EMBL:ABC44609.1, ECO:0000313|Proteomes:UP000008674}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 13855 / CECT 5946 / M31
RC   {ECO:0000313|Proteomes:UP000008674};
RX   PubMed=16330755; DOI=10.1073/pnas.0509073102;
RA   Mongodin E.F., Nelson K.E., Daugherty S., Deboy R.T., Wister J., Khouri H.,
RA   Weidman J., Walsh D.A., Papke R.T., Sanchez Perez G., Sharma A.K.,
RA   Nesbo C.L., MacLeod D., Bapteste E., Doolittle W.F., Charlebois R.L.,
RA   Legault B., Rodriguez-Valera F.;
RT   "The genome of Salinibacter ruber: convergence and gene exchange among
RT   hyperhalophilic bacteria and archaea.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:18147-18152(2005).
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DR   EMBL; CP000159; ABC44609.1; -; Genomic_DNA.
DR   RefSeq; YP_446857.1; NC_007677.1.
DR   AlphaFoldDB; Q2RYX4; -.
DR   STRING; 309807.SRU_2765; -.
DR   ESTHER; salrd-q2ryx4; DPP4N_Peptidase_S9.
DR   EnsemblBacteria; ABC44609; ABC44609; SRU_2765.
DR   KEGG; sru:SRU_2765; -.
DR   PATRIC; fig|309807.25.peg.2883; -.
DR   eggNOG; COG0823; Bacteria.
DR   eggNOG; COG1506; Bacteria.
DR   HOGENOM; CLU_006105_3_1_10; -.
DR   OrthoDB; 9812921at2; -.
DR   Proteomes; UP000008674; Chromosome.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR001375; Peptidase_S9.
DR   InterPro; IPR002470; Peptidase_S9A.
DR   InterPro; IPR002469; Peptidase_S9B_N.
DR   PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR   Pfam; PF00930; DPPIV_N; 1.
DR   Pfam; PF00326; Peptidase_S9; 1.
DR   PRINTS; PR00862; PROLIGOPTASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008674}.
FT   DOMAIN          329..627
FT                   /note="Dipeptidylpeptidase IV N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00930"
FT   DOMAIN          718..915
FT                   /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00326"
FT   REGION          217..248
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          343..363
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        233..248
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   939 AA;  105582 MW;  699A1EBA73677F71 CRC64;
     MGSSPRSAGA ADSGRDAIHG WSPLAVAFEG GSDVACVWFS PHIPSSRLPV SSKLSSMHLS
     FVRSSFVSRC SSTRVSTCPL LLVGAVLMAV VVGRPAAPAF GQEAADEEGR VGGPGAANYE
     LAERFAPYKV EDMAYDLTVD LQWIEGREGF WYDFETAEGT RYWIVDPEDG TQRELFDRER
     LASELTRITQ DPWDAKHLPI ENIRFVDENT LQFDVTSSQE VKDEDVEDVE EEQQKQDKEG
     AGADEETEQK VFHFEYDVTT QTLRELEDYE EPDDHPDWAN VSPDGETVVF ARNYDLWMMD
     GAAYEKVLDA RRGEDGEDAE EAVEELDLEE TRLTEDGEKY YSYAANNDGR GKTDTKKQEE
     KGERKAVDIS WAKDSRRFAL VRSDLRDVEE LWVVHATGND RPELETFKYP MPGEDSVGRD
     ELWIYDLEAM EKTRVADTGW TDQSLSILDD RQFRYPGSEA PRRRVWLSEG SDALWYERHS
     RDRTKADLVV ADAETGEIER TVVEERFNKY FHTQRPELLS NGDVLWLSER DGWSHLYRYG
     SDGTVEAQLT EGDWHVDAVK AVDEEEGVAY VSGNGREAGE DPYYDHLYRV QLDGSGVELL
     NPGDADHSAT MNESARFFVD NHSRVDTVPR AVLRNAEGEV VTELQTADLS SLNEAGWQMP
     EPFEVTAADG VTDLHGVMYK PFDFDPEKEY PVITYVYPGP QTEAVPKAFA PSGDEVGLAQ
     LGFIVVVAGH RGGHPDRSRW YHTYGYGNLR DYPLADKKAT IEQLAARHDF IDGDRVGIYG
     HSGGGFLTTA SLLQYPDVFD VGVASSGNHE NNVYNRWWAE THHGVEPTEN DSGEVSFDFS
     IGKNSELAGN LEGDLLLTTG TIDNNVHPAN TYRMAKALIE AGKRFDLFVF PGQRHGYGSM
     DDYWFWLRAE YFAEHLLSDG RDRPNVAPLQ QETPASERP
//