ID Q2TR59_ACIBA Unreviewed; 275 AA.
AC Q2TR59;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:AAW57528.1, ECO:0000313|EMBL:MDK4883890.1};
DE SubName: Full=AraC1 {ECO:0000313|EMBL:ABO33300.1};
GN Name=trr {ECO:0000313|EMBL:AAW57528.1};
GN Synonyms=araC1 {ECO:0000313|EMBL:ABO33300.1};
GN ORFNames=FR761_18630 {ECO:0000313|EMBL:QFH47330.1}, P9867_20370
GN {ECO:0000313|EMBL:MDK4883890.1};
OS Acinetobacter baumannii.
OG Plasmid pAb242 {ECO:0000313|EMBL:AKJ75402.1},
OG Plasmid pE47_001 {ECO:0000313|EMBL:QFH47330.1},
OG Plasmid pWA3 {ECO:0000313|EMBL:AFF18252.1}, and
OG Plasmid pe47_001 {ECO:0000313|Proteomes:UP000327158}.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter; Acinetobacter calcoaceticus/baumannii complex.
OX NCBI_TaxID=470 {ECO:0000313|EMBL:AAW57528.1};
RN [1] {ECO:0000313|EMBL:AAW57528.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MAD {ECO:0000313|EMBL:AAW57528.1};
RX PubMed=15504844; DOI=10.1128/AAC.48.11.4217-4225.2004;
RA Girlich D., Naas T., Nordmann P.;
RT "OXA-60, a chromosomal, inducible, and imipenem-hydrolyzing class D beta-
RT lactamase from Ralstonia pickettii.";
RL Antimicrob. Agents Chemother. 48:4217-4225(2004).
RN [2] {ECO:0000313|EMBL:AAW57528.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MAD {ECO:0000313|EMBL:AAW57528.1};
RX PubMed=15616297; DOI=10.1128/AAC.49.1.202-208.2005;
RA Poirel L., Marque S., Heritier C., Segonds C., Chabanon G., Nordmann P.;
RT "OXA-58, a novel class D {beta}-lactamase involved in resistance to
RT carbapenems in Acinetobacter baumannii.";
RL Antimicrob. Agents Chemother. 49:202-208(2005).
RN [3] {ECO:0000313|EMBL:AAW57528.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MAD {ECO:0000313|EMBL:AAW57528.1};
RX PubMed=16569863; DOI=10.1128/AAC.50.4.1442-1448.2006;
RA Poirel L., Nordmann P.;
RT "Genetic structures at the origin of acquisition and expression of the
RT carbapenem-hydrolyzing oxacillinase gene blaOXA-58 in Acinetobacter
RT baumannii.";
RL Antimicrob. Agents Chemother. 50:1442-1448(2006).
RN [4] {ECO:0000313|EMBL:ABO33300.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=10 {ECO:0000313|EMBL:ABO33300.1};
RX PubMed=18299404; DOI=10.1128/AAC.00978-07;
RA Poirel L., Mansour W., Bouallegue O., Nordmann P.;
RT "Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia
RT producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97.";
RL Antimicrob. Agents Chemother. 52:1613-1617(2008).
RN [5] {ECO:0000313|EMBL:AFF18252.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WA3 {ECO:0000313|EMBL:AFF18252.1};
RC PLASMID=pWA3 {ECO:0000313|EMBL:AFF18252.1};
RX PubMed=24400107;
RA Fu Y., Jiang J., Zhou H., Jiang Y., Fu Y., Yu Y., Zhou J.;
RT "Characterization of a Novel Plasmid Type and Various Genetic Contexts of
RT bla OXA-58 in Acinetobacter spp. from Multiple Cities in China.";
RL PLoS ONE 9:E84680-E84680(2014).
RN [6] {ECO:0000313|EMBL:AKJ75402.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Ab242 {ECO:0000313|EMBL:AKJ75402.1};
RC PLASMID=pAb242 {ECO:0000313|EMBL:AKJ75402.1};
RA Cameranesi M.M., Moran-Barrio J., Limansky A.S., Viale A.M.;
RT "Characterization of a novel plasmid-borne genetic platform driving blaOXA-
RT 58 and aphA6 dissemination in Acinetobacter baumannii clinical strains of
RT Argentina.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|EMBL:QFH47330.1, ECO:0000313|Proteomes:UP000327158}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E47 {ECO:0000313|EMBL:QFH47330.1,
RC ECO:0000313|Proteomes:UP000327158};
RC PLASMID=pe47_001 {ECO:0000313|Proteomes:UP000327158}, and pE47_001
RC {ECO:0000313|EMBL:QFH47330.1};
RA Phan H.T.T., Stoesser N., Gordon K.A., Crook D., Walker S.A., Mathers A.J.,
RA Peto T.E.A., George S., Lipworth S.I.;
RT "Genomic Dynamics of Species and Mobile Genetic Elements in a Prolonged
RT blaIMP-4-associated Carbapenemase Outbreak in an Australian Hospital.";
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
RN [8] {ECO:0000313|EMBL:MDK4883890.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CPO519 {ECO:0000313|EMBL:MDK4883890.1};
RA Macesic N.;
RT "Genomic dissection of endemic carbapenem resistance: metallo-beta-
RT lactamase gene dissemination through clonal, plasmid and integron transfer
RT pathways.";
RL Submitted (JAN-2023) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AY665723; AAW57528.1; -; Genomic_DNA.
DR EMBL; EF102240; ABO33300.1; -; Genomic_DNA.
DR EMBL; JQ241791; AFF18252.1; -; Genomic_DNA.
DR EMBL; KR055667; AKJ75402.1; -; Genomic_DNA.
DR EMBL; JARTMM010000162; MDK4883890.1; -; Genomic_DNA.
DR EMBL; CP042557; QFH47330.1; -; Genomic_DNA.
DR RefSeq; WP_000073658.1; NZ_VHGO01000071.1.
DR PATRIC; fig|470.1346.peg.3242; -.
DR Proteomes; UP000327158; Plasmid pe47_001.
DR Proteomes; UP001174156; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR003313; AraC-bd.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR037923; HTH-like.
DR InterPro; IPR018060; HTH_AraC.
DR PANTHER; PTHR46796; HTH-TYPE TRANSCRIPTIONAL ACTIVATOR RHAS-RELATED; 1.
DR PANTHER; PTHR46796:SF16; TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR Pfam; PF02311; AraC_binding; 1.
DR Pfam; PF12833; HTH_18; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR SUPFAM; SSF51215; Regulatory protein AraC; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE 4: Predicted;
KW Plasmid {ECO:0000313|EMBL:AFF18252.1};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 170..267
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
SQ SEQUENCE 275 AA; 31930 MW; 98E0D9A8BC2E4FA3 CRC64;
MSNWVNVTQD KSTGIELIHA HFKGFAYDPH LHSSYLIGVT ELGHQQFNCR KKIIDSYQGQ
TFMLEPEEVH DGNAPDPLGF TYKMMHLDPA WLKKSYEGIF NEPIELAIES TLRSDPQLSH
LILSTYNILN NNESQLMKDT YLDLLLENLV NKKILYKREK SIQTLPNIAL KLKEILHESL
FHDLDLQTLS TLVKTDRFYI NRVFKKNFNC SPHQYLIQLR LNKAKELLRK GLSATTVASY
LCFSDQSHLG RWFKRCYGIT LNQYQKACTN VLDIS
//
