ID Q2UKU9_ASPOR Unreviewed; 570 AA.
AC Q2UKU9;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 24-JAN-2024, entry version 84.
DE RecName: Full=Glutamate decarboxylase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AO090003000666 {ECO:0000313|EMBL:BAE57816.1};
OS Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=510516 {ECO:0000313|EMBL:BAE57816.1, ECO:0000313|Proteomes:UP000006564};
RN [1] {ECO:0000313|EMBL:BAE57816.1, ECO:0000313|Proteomes:UP000006564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42149 / RIB 40 {ECO:0000313|Proteomes:UP000006564};
RX PubMed=16372010; DOI=10.1038/nature04300;
RA Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA Takahashi M., Takase K., Terabayashi Y., Wortman J., Yamada O.,
RA Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA Kikuchi H.;
RT "Genome sequencing and analysis of Aspergillus oryzae.";
RL Nature 438:1157-1161(2005).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR602129-50, ECO:0000256|RuleBase:RU000382};
CC -!- SIMILARITY: Belongs to the group II decarboxylase family.
CC {ECO:0000256|RuleBase:RU000382}.
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DR EMBL; AP007155; BAE57816.1; -; Genomic_DNA.
DR RefSeq; XP_001819818.1; XM_001819766.1.
DR AlphaFoldDB; Q2UKU9; -.
DR STRING; 510516.Q2UKU9; -.
DR EnsemblFungi; BAE57816; BAE57816; AO090003000666.
DR GeneID; 5991801; -.
DR KEGG; aor:AO090003000666; -.
DR VEuPathDB; FungiDB:AO090003000666; -.
DR HOGENOM; CLU_011856_0_0_1; -.
DR OMA; RHATYHA; -.
DR OrthoDB; 888358at2759; -.
DR Proteomes; UP000006564; Chromosome 2.
DR GO; GO:0016830; F:carbon-carbon lyase activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR Gene3D; 3.90.1150.170; -; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR PANTHER; PTHR45677:SF8; CYSTEINE SULFINIC ACID DECARBOXYLASE; 1.
DR PANTHER; PTHR45677; GLUTAMATE DECARBOXYLASE-RELATED; 1.
DR Pfam; PF00282; Pyridoxal_deC; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU000382};
KW Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR602129-50,
KW ECO:0000256|RuleBase:RU000382};
KW Reference proteome {ECO:0000313|Proteomes:UP000006564}.
FT MOD_RES 325
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR602129-50"
SQ SEQUENCE 570 AA; 61819 MW; DB7214EB18127772 CRC64;
MAVSPPSRRA EEVRSLLSAV EDLLIPFIRS ADEDPLGQKA LENGVNGANG THNDLKPSGT
SLVDHKKPEE LQSILQLELP EQGTGQDGLV EALQKVLRYS VNTWHQGFLD KLYASTNAPG
VASELILAAL NTNVHVYQVS PALTVIEKFT GKQLASLFGL KGPRAGGISV QGGSASNTTS
IVIARNNLFP ATKRDGNGDY RFVLFTSAHG HYSIEKAAQM LGLGSSSVWS VPIDKQGRMI
PAELENLVRK ALKENRTPFY VNATAGTTVM GSFDPFDEIA AICKKYNLWF HVDGSWGGSF
VFSKRQRQKL AGAEKADSIA INPHKMLGVP VTCSFLLAAD LRRFHRANTL PAGYLFHNED
TELPEANGCN GAVESELSVD SPEVWDLADL TLQCGRRADS LKLFLGWTYY GTAGYEKQID
AACDIAAHLA TLVAENPNFI LVSENPPPCL QVCFYYAPGG QFLHPRGVVS DEAERGKANS
KVTEQVTHAI VSKGFMVDFA PPSGDDDVVG NGKFFRCVVN VQTTKETVEA LLQAIEEVGP
GIVENMKVQK AQRKFNRPGE RGHGPVVHHP
//
