ID CIAO1_ASPOR Reviewed; 438 AA.
AC Q2UPI0;
DT 01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 24-JAN-2024, entry version 107.
DE RecName: Full=Probable cytosolic iron-sulfur protein assembly protein 1 {ECO:0000255|HAMAP-Rule:MF_03037};
GN Name=cia1; ORFNames=AO090005001633;
OS Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=510516;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42149 / RIB 40;
RX PubMed=16372010; DOI=10.1038/nature04300;
RA Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O.,
RA Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA Kikuchi H.;
RT "Genome sequencing and analysis of Aspergillus oryzae.";
RL Nature 438:1157-1161(2005).
CC -!- FUNCTION: Essential component of the cytosolic iron-sulfur (Fe/S)
CC protein assembly machinery. Required for the maturation of
CC extramitochondrial Fe/S proteins. {ECO:0000255|HAMAP-Rule:MF_03037}.
CC -!- SIMILARITY: Belongs to the WD repeat CIA1 family. {ECO:0000255|HAMAP-
CC Rule:MF_03037}.
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DR EMBL; AP007151; BAE56535.1; -; Genomic_DNA.
DR AlphaFoldDB; Q2UPI0; -.
DR SMR; Q2UPI0; -.
DR STRING; 510516.Q2UPI0; -.
DR EnsemblFungi; BAE56535; BAE56535; AO090005001633.
DR VEuPathDB; FungiDB:AO090005001633; -.
DR HOGENOM; CLU_000288_57_8_1; -.
DR OMA; IREIRWS; -.
DR OrthoDB; 5486866at2759; -.
DR Proteomes; UP000006564; Chromosome 1.
DR GO; GO:0097361; C:CIA complex; IEA:InterPro.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR HAMAP; MF_03037; ciao1; 1.
DR InterPro; IPR028608; CIAO1/Cia1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19920:SF0; CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED; 1.
DR PANTHER; PTHR19920; WD40 PROTEIN CIAO1; 1.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Reference proteome; Repeat; WD repeat.
FT CHAIN 1..438
FT /note="Probable cytosolic iron-sulfur protein assembly
FT protein 1"
FT /id="PRO_0000382505"
FT REPEAT 15..57
FT /note="WD 1"
FT REPEAT 61..103
FT /note="WD 2"
FT REPEAT 140..179
FT /note="WD 3"
FT REPEAT 187..226
FT /note="WD 4"
FT REPEAT 254..297
FT /note="WD 5"
FT REPEAT 327..366
FT /note="WD 6"
FT REPEAT 396..438
FT /note="WD 7"
FT REGION 290..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..310
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 438 AA; 48857 MW; 5FC3E603AF02C840 CRC64;
MTENPTASLT LLSDLTPPSL ERTWLTAPHP SLPIVATCSS DKTVRVYSLT NFRLLSTISG
GHKRSVRTCA WKPHVQGESV LATGSFDATV GIWRRWDSYG RAEDGTDVRG LSSETLDGNG
RDTQEYEDDE EWRFAVLLDG HDSEVKSVSW SPSGMLLATC SRDKSIWIWE DLDDGDNNFE
TVAVMQEHEG DVKCVAWHPV EECLASASYD NTIRLWREDI DDWGQVACIK GHTGTVWYLD
WEGIGNVPST AAVCEQGTSL SAEWKDQRAM SGPRLASCSD DRTVRIWKRR PKEQRAQSQV
GSTGIPSIIR PTGTDETWEE DVLLPQIHEL SIYAVAWSKR TGLLASVGAD GRIVVYEELF
LTSPARTPDT NTPTDTSAII PRTHTEWVAI AILEGAHGIY EVNHVAWARR ADRCRKENEE
VLITTADDGS IKVWTLRR
//
