ID   Q2UWW9_STAAU            Unreviewed;       461 AA.
AC   Q2UWW9;
DT   24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT   24-JAN-2006, sequence version 1.
DT   24-JAN-2024, entry version 52.
DE   SubName: Full=Fibronectin binding protein A {ECO:0000313|EMBL:CAJ27662.1};
DE   Flags: Fragment;
GN   Name=fnbA {ECO:0000313|EMBL:CAJ27662.1};
OS   Staphylococcus aureus.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=1280 {ECO:0000313|EMBL:CAJ27662.1};
RN   [1] {ECO:0000313|EMBL:CAJ27662.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=1150-93 {ECO:0000313|EMBL:CAJ27662.1};
RX   PubMed=16352833; DOI=10.1128/JB.188.1.169-178.2006;
RA   Kuhn G., Francioli P., Blanc D.S.;
RT   "Evidence for clonal evolution among highly polymorphic genes in
RT   methicillin-resistant Staphylococcus aureus.";
RL   J. Bacteriol. 188:169-178(2006).
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall
CC       {ECO:0000256|ARBA:ARBA00004168}; Peptidoglycan-anchor
CC       {ECO:0000256|ARBA:ARBA00004168}.
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DR   EMBL; AM076025; CAJ27662.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2UWW9; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   Gene3D; 2.60.40.1280; -; 1.
DR   Gene3D; 2.60.40.1290; -; 1.
DR   InterPro; IPR011266; Adhesin_Fg-bd_dom_2.
DR   InterPro; IPR008966; Adhesion_dom_sf.
DR   InterPro; IPR011252; Fibrogen-bd_dom1.
DR   InterPro; IPR041171; SDR_Ig.
DR   Pfam; PF17961; Big_8; 1.
DR   Pfam; PF10425; SdrG_C_C; 1.
DR   SUPFAM; SSF49401; Bacterial adhesins; 2.
PE   4: Predicted;
KW   Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW   Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          96..193
FT                   /note="SDR-like Ig"
FT                   /evidence="ECO:0000259|Pfam:PF17961"
FT   DOMAIN          220..375
FT                   /note="Fibrinogen-binding"
FT                   /evidence="ECO:0000259|Pfam:PF10425"
FT   REGION          1..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..51
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CAJ27662.1"
FT   NON_TER         461
FT                   /evidence="ECO:0000313|EMBL:CAJ27662.1"
SQ   SEQUENCE   461 AA;  50971 MW;  8AAC8C17F7E1DAA0 CRC64;
     KPQVKETTQS QDNSGDQRQV DLIPKKATQN QVAETQVEVA QPRTVSESKP RVTRSADVVE
     AKEGMGVSEV KGTDVTSKVT VESGSIEAPQ GNKVEPHAGR RVVLKYKLKF ADGLKRGDYF
     DFTLSNNVNT YGVSTARKVP EIKNGSVVMA TGEILGNGNI RYTFTNEIEH KVEVTANLEI
     NLFIDPKTVQ SNGEQKITSK LNGEETEKTI PVVYNPGVSN SYTNVNGSIE TFNKESNKFT
     HIAYIKPMNG NQSNTVSVTG TLTEGSNLAG GQPTVKVYEY LGKKDELPQS VYANTSDTNK
     FKDVTNEMNG KLSVQDNGSY SLNLDKLDKT YVIHYTGEYL QGSDQVNFRT ELYGYPERAY
     KSYYVYGGYR LTWDNGLVLY SNKADGNGKN GQIIQNNDFE YKEDTAKGTM SGQYDAKQII
     ETEENQDNTP LDIDYHTAID GEGGYVDGYI ETIEETDSSA I
//