ID   Q2YE85_EPTST            Unreviewed;       323 AA.
AC   Q2YE85;
DT   20-DEC-2005, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2005, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=Variable lymphocyte receptor A {ECO:0000313|EMBL:ABB59062.1};
GN   Name=VLRA {ECO:0000313|EMBL:ABB59062.1};
OS   Eptatretus stoutii (Pacific hagfish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata; Myxini;
OC   Myxiniformes; Myxinidae; Eptatretinae; Eptatretus.
OX   NCBI_TaxID=7765 {ECO:0000313|EMBL:ABB59062.1};
RN   [1] {ECO:0000313|EMBL:ABB59062.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=15964979; DOI=10.1073/pnas.0503792102;
RA   Pancer Z., Saha N.R., Kasamatsu J., Suzuki T., Amemiya C.T., Kasahara M.,
RA   Cooper M.D.;
RT   "Variable lymphocyte receptors in hagfish.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:9224-9229(2005).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY964784; ABB59062.1; -; mRNA.
DR   AlphaFoldDB; Q2YE85; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR   PANTHER; PTHR24373:SF275; VASORIN; 1.
DR   Pfam; PF13855; LRR_8; 1.
DR   SMART; SM00369; LRR_TYP; 5.
DR   SUPFAM; SSF52058; L domain-like; 1.
PE   2: Evidence at transcript level;
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:ABB59062.1};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..323
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004218926"
FT   TRANSMEM        296..317
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   323 AA;  35206 MW;  D3A0F17141C7E548 CRC64;
     MMGPVLAACL LIILSTAWIS QANGATCKKD GGVCTCNDQT KNVDCSSKGL TAIPSNIPVD
     TNRLLLGSNK LSSLSAKAFH NLNKLTFLSL GTNQLQALPV GVFDHLVSLD KLVLTSNKLK
     SLPPRVFDSL TKLTYLSLGS NQLQRLPEGV FDKLTELKTL NLDINQLRRV PEGIFDSLSS
     LSTVRLQSNP WDCSCRDILY LSNWIREKKG TVSNIEAAEC DGGTKAVLEI TEEEAAEDCV
     YPNTTTAIPT TIITTLASSN DDDIPELPVP QENFQKFLGY QEPDHLPTQP QCLMSISGYL
     GLMMSLVLTS AAILYVIHFL KKA
//