ID Q388B5_TRYB2 Unreviewed; 517 AA.
AC Q388B5;
DT 22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2005, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=Sarcoplasmic reticulum glycoprotein, putative {ECO:0000313|EMBL:EAN78857.1};
GN ORFNames=Tb10.61.1710 {ECO:0000313|EMBL:EAN78857.1};
OS Trypanosoma brucei brucei (strain 927/4 GUTat10.1).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX NCBI_TaxID=185431 {ECO:0000313|EMBL:EAN78857.1, ECO:0000313|Proteomes:UP000008524};
RN [1] {ECO:0000313|EMBL:EAN78857.1, ECO:0000313|Proteomes:UP000008524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:EAN78857.1,
RC ECO:0000313|Proteomes:UP000008524};
RX PubMed=16020726; DOI=10.1126/science.1112642;
RA Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H.,
RA Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U.,
RA Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B.,
RA Alsmark U.C., Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F.,
RA Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C.,
RA Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A.,
RA Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D.,
RA Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D.,
RA Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S.,
RA Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S.,
RA Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G.,
RA Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A.,
RA Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M.,
RA Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S.,
RA Walker D., Wanless D., Wang S., White B., White O., Whitehead S.,
RA Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E.,
RA Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E.,
RA Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.;
RT "The genome of the African trypanosome Trypanosoma brucei.";
RL Science 309:416-422(2005).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004413};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}.
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DR EMBL; CM000208; EAN78857.1; -; Genomic_DNA.
DR RefSeq; XP_827969.1; XM_822876.1.
DR AlphaFoldDB; Q388B5; -.
DR PaxDb; 5691-EAN78857; -.
DR GeneID; 3662856; -.
DR KEGG; tbr:Tb10.61.1710; -.
DR VEuPathDB; TriTrypDB:Tb927.10.14910; -.
DR eggNOG; KOG1954; Eukaryota.
DR InParanoid; Q388B5; -.
DR OMA; LMIGQYS; -.
DR OrthoDB; 12127at2759; -.
DR Proteomes; UP000008524; Chromosome 10.
DR GO; GO:0005737; C:cytoplasm; IDA:GeneDB.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0016529; C:sarcoplasmic reticulum; ISA:GeneDB.
DR GO; GO:0005509; F:calcium ion binding; ISA:GeneDB.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IBA:GO_Central.
DR GO; GO:0016197; P:endosomal transport; ISA:GeneDB.
DR CDD; cd09913; EHD; 1.
DR Gene3D; 1.10.268.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR040990; DUF5600.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43681:SF1; SARCALUMENIN; 1.
DR PANTHER; PTHR43681; TRANSMEMBRANE GTPASE FZO; 1.
DR Pfam; PF18150; DUF5600; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008524}.
FT DOMAIN 59..290
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
SQ SEQUENCE 517 AA; 59421 MW; AF831EEFB486CBB0 CRC64;
MSSGNRDLSV DNPLQWRDLN NTEEFMRKLH EIYMKSVKPL EDIYLYEVLS PRWFEETLSS
YKPIVTFLGP WSAGKSTFIN YLLQDNYLFT GPQPTTSEFT VITYGDDVTT LDGHVVASTK
DLPFRALANF GEGFMGNFCG LQVPHELLKR VVLVDTPGVL ENSTDDRERR YNYTEVCRWF
VERSDMVFLL FDPAKLDAGT ELRNLFRYTF KGMEGKLRIV LNKADSVAKK ELMRVYGSLF
WNLSTLIRCT EPPRVYIGSF WDQPYKPGTF ALLFTKEKED LLYELTELVP RQARDRKVAA
LISHAKKVVC HAYIVGGIRA DLPMFFGKEK AKRKALENLP KTYQLVASRN RLSPKDLPPA
QLYHEYFEKV HLEKLPDIKK VEKTGMITTA QHYICNILPS MFYPMKQVPV PDPRNKTEQG
KLREMYYGGL RDQYDGKEGK QGSSDTVPIA FRETALGPNP ELRGGCGQLT VPGATANTTP
AMNNVQMNEQ QQQMLMQMMM MMQQQQQQGN NQFYAPR
//
