ID Q39246_ARATH Unreviewed; 272 AA.
AC Q39246;
DT 01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1996, sequence version 1.
DT 22-FEB-2023, entry version 102.
DE RecName: Full=phosphoribosylanthranilate isomerase {ECO:0000256|ARBA:ARBA00012572};
DE EC=5.3.1.24 {ECO:0000256|ARBA:ARBA00012572};
GN Name=PAI4 {ECO:0000313|EMBL:AAB03500.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AAB03500.1};
RN [1] {ECO:0000313|EMBL:AAB03500.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Wassilewskija {ECO:0000313|EMBL:AAB03500.1};
RX PubMed=8521489; DOI=10.1016/0092-8674(95)90185-X;
RA Bender J., Fink G.R.;
RT "Epigenetic control of an endogenous gene family is revealed by a novel
RT blue fluorescent mutant of Arabidopsis.";
RL Cell 83:725-734(1995).
CC -!- PATHWAY: Amino-acid biosynthesis; L-tryptophan biosynthesis; L-
CC tryptophan from chorismate: step 3/5. {ECO:0000256|ARBA:ARBA00004664}.
CC -!- SIMILARITY: Belongs to the TrpF family.
CC {ECO:0000256|ARBA:ARBA00007571}.
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DR EMBL; U34757; AAB03500.1; -; Genomic_DNA.
DR AlphaFoldDB; Q39246; -.
DR UniPathway; UPA00035; UER00042.
DR GO; GO:0004640; F:phosphoribosylanthranilate isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0000162; P:tryptophan biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00405; PRAI; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR HAMAP; MF_00135; PRAI; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR001240; PRAI_dom.
DR InterPro; IPR011060; RibuloseP-bd_barrel.
DR InterPro; IPR044643; TrpF_fam.
DR PANTHER; PTHR42894; N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE; 1.
DR PANTHER; PTHR42894:SF1; N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE; 1.
DR Pfam; PF00697; PRAI; 1.
DR SUPFAM; SSF51366; Ribulose-phoshate binding barrel; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000313|EMBL:AAB03500.1}.
FT DOMAIN 68..265
FT /note="N-(5'phosphoribosyl) anthranilate isomerase (PRAI)"
FT /evidence="ECO:0000259|Pfam:PF00697"
SQ SEQUENCE 272 AA; 29485 MW; 0C53E9B99A150B9F CRC64;
MSTGISTDLH VHFGALNFSK TYKSGLRNRT VSFSRVGYAQ NRKLSCSVSN TENVAPKDDE
RGKDRPLVKM CGITSARDAA MAVEAGADLI GMIIWPHSKR SISLSIAKDI SKVAREGGAK
PVGVFVEDDE NTILRAADYS DLELVQLHGN GSRAAFSRLV RKRRVIYVLN ANQDGKLLNE
VPEEDCHLAD WILVDSATGG SGHGFNWAQF KLPSVRSRNG WLLAGGINPT NVSEALSILQ
PDGIDVSSGI CGIQKDKSKI SSFITAVRSV HY
//
