ID Q3AEJ7_CARHZ Unreviewed; 672 AA.
AC Q3AEJ7;
DT 22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2005, sequence version 1.
DT 27-MAR-2024, entry version 113.
DE SubName: Full=Sigma-54 dependent transcriptional regulator {ECO:0000313|EMBL:ABB13691.1};
GN OrderedLocusNames=CHY_0581 {ECO:0000313|EMBL:ABB13691.1};
OS Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 /
OS Z-2901).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Carboxydothermus.
OX NCBI_TaxID=246194 {ECO:0000313|EMBL:ABB13691.1, ECO:0000313|Proteomes:UP000002706};
RN [1] {ECO:0000313|EMBL:ABB13691.1, ECO:0000313|Proteomes:UP000002706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-161 / DSM 6008 / Z-2901
RC {ECO:0000313|Proteomes:UP000002706};
RX PubMed=16311624; DOI=10.1371/journal.pgen.0010065;
RA Wu M., Ren Q., Durkin A.S., Daugherty S.C., Brinkac L.M., Dodson R.J.,
RA Madupu R., Sullivan S.A., Kolonay J.F., Haft D.H., Nelson W.C.,
RA Tallon L.J., Jones K.M., Ulrich L.E., Gonzalez J.M., Zhulin I.B.,
RA Robb F.T., Eisen J.A.;
RT "Life in hot carbon monoxide: the complete genome sequence of
RT Carboxydothermus hydrogenoformans Z-2901.";
RL PLoS Genet. 1:563-574(2005).
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DR EMBL; CP000141; ABB13691.1; -; Genomic_DNA.
DR RefSeq; WP_011343513.1; NC_007503.1.
DR AlphaFoldDB; Q3AEJ7; -.
DR STRING; 246194.CHY_0581; -.
DR KEGG; chy:CHY_0581; -.
DR eggNOG; COG3290; Bacteria.
DR eggNOG; COG3829; Bacteria.
DR HOGENOM; CLU_000445_8_1_9; -.
DR InParanoid; Q3AEJ7; -.
DR OrthoDB; 9803970at2; -.
DR Proteomes; UP000002706; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR32071:SF57; SIGMA L-DEPENDENT TRANSCRIPTIONAL REGULATOR YQIR-RELATED; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00989; PAS; 2.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 2.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002706};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 108..156
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 169..222
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 226..282
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 359..589
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
SQ SEQUENCE 672 AA; 74697 MW; 08D057C397B4E393 CRC64;
MEAIKILLLG LGQGGTRFLK ILGKKSNLKL MAVEKNPEAL GVKIAKDLNI PVFSTLEEGL
TKAPNLIIDT TGDPQIEKTL KNLKENIPYL SGYIAKLFIS LADELFYQEK ELEAIINSAH
DGLIAVNREG IITWFNSAAE KITGINRNQA LGKYVVDAIP NTRLHVILKT GKAEINQFQD
LGQAKIITSR IPLFNEFGEV IGAFAIFKDI TDMQKLAEEL TNLQEIKTLL TSIIDCTQDA
ISVVDERGYG LLINKAYSEL TGLTEKDVIG KPATVDIAEG ESVHFRVLQE KRPIKNITMK
VGPLKKEVVV NAAPLIVDGT LKGSVAVIHD VSELKRLTEE IDRLKRSLAS SARYTFDDII
GEHPLLISAI ELAKLAAQTS ATVLLRGESG TGKELFAHAI HNQSPRAKKP FIRINCAALT
ESLLESELFG YEEGAFTGAK KGGKKGVFEE ANGGTLFLDE ITTLSSNLQA KLLRVLQEKE
IVRVGGNQPI PVDVRIIAAT NLNLEEAVKN KTFREDLYYR INVIPINLPA LRERKTDIPA
LARAIVQKLN REYGRNIKFI DPEVFRYLMS YSWPGNIREL ENYLGRAMLK VSLAENRLGP
EHLPKLFEET PQTSFSKTQS SDLNLKKLTR EFEKSVVKEA LEKAKYNKTK AAQLLGITPR
SLYNKLKEFD LL
//
