ID   Q3ASJ8_CHLCH            Unreviewed;       912 AA.
AC   Q3ASJ8;
DT   22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2005, sequence version 1.
DT   27-MAR-2024, entry version 79.
DE   RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE            EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN   OrderedLocusNames=Cag_0759 {ECO:0000313|EMBL:ABB28027.1};
OS   Chlorobium chlorochromatii (strain CaD3).
OC   Bacteria; Chlorobiota; Chlorobiia; Chlorobiales; Chlorobiaceae;
OC   Chlorobium/Pelodictyon group; Chlorobium.
OX   NCBI_TaxID=340177 {ECO:0000313|EMBL:ABB28027.1};
RN   [1] {ECO:0000313|EMBL:ABB28027.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CaD3 {ECO:0000313|EMBL:ABB28027.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Bryant D., Schmutz J., Larimer F.,
RA   Land M., Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of Chlorobium chlorochromatii CaD3.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC         N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC         homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC         COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC         Evidence={ECO:0000256|ARBA:ARBA00001279};
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DR   EMBL; CP000108; ABB28027.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q3ASJ8; -.
DR   STRING; 340177.Cag_0759; -.
DR   REBASE; 11468; CchORF759P.
DR   KEGG; cch:Cag_0759; -.
DR   eggNOG; COG1002; Bacteria.
DR   HOGENOM; CLU_005831_3_0_10; -.
DR   OrthoDB; 593376at2; -.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR046818; MmeI_C.
DR   InterPro; IPR046819; MmeI_hel.
DR   InterPro; IPR046816; MmeI_Mtase.
DR   InterPro; IPR046817; MmeI_N.
DR   InterPro; IPR046820; MmeI_TRD.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR33841:SF6; DNA METHYLTRANSFERASE A; 1.
DR   PANTHER; PTHR33841; DNA METHYLTRANSFERASE YEEA-RELATED; 1.
DR   Pfam; PF20467; MmeI_C; 1.
DR   Pfam; PF20465; MmeI_hel; 1.
DR   Pfam; PF20473; MmeI_Mtase; 1.
DR   Pfam; PF20464; MmeI_N; 1.
DR   Pfam; PF20466; MmeI_TRD; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          1..159
FT                   /note="MmeI-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF20464"
FT   DOMAIN          175..252
FT                   /note="MmeI-like helicase spacer"
FT                   /evidence="ECO:0000259|Pfam:PF20465"
FT   DOMAIN          339..592
FT                   /note="MmeI-like DNA-methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF20473"
FT   DOMAIN          609..812
FT                   /note="MmeI-like target recognition"
FT                   /evidence="ECO:0000259|Pfam:PF20466"
FT   DOMAIN          815..891
FT                   /note="MmeI-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF20467"
SQ   SEQUENCE   912 AA;  104801 MW;  A5B32C48C02FBFE9 CRC64;
     MNIAQIENNL QQLVKTFNEE SFIYDLLLAY GQPKATIKRI KDGGLNLSKV EGEIAWKKKL
     FFKTVKGVDL HELIADLTEN GKAIKHDPRF IIVTDYKNIL AIDTKTQDTL DIEILEIAKH
     FDFFLPWAGM EKFQHQNENL ADVRAAEKMA KLYDDIKKDN PISTSSIAEQ KAEIHNLNVF
     LSRLLFCFFA EDTGIFEKAQ FTNAISSHTQ QDGSDLNSYL DNLFDIMNMP NKQRENLPAY
     LLAFPYVNGG LFRSKHYAPK FTHKSRKAII DSGELDWSAI NPDIFGSMIQ AVITPEHRGG
     LGMHYTSVPN IMKVIEPLFL NELYEEFDVA NSTSSVSVKN KKLNALLLRI WNIKIFDPAC
     GSGNFLIIAY KELRKLEILI FKEIAKNNHN YSAQLSGISL GNFYGIELDD FAHEVSILSL
     WLAEHQMNQI FFKEFGRTKP ALPLTETGNI VHGNATRLDW ENVCPKEEGD EIYILGNPPY
     LGSRNQDDLQ KADMKTAFKD DYKSLDYIAC WLLKGADFIE NFHAQFAFVS TNSICQGEQV
     ALIWPRVLKE NLEIGFAHNA FKWSNNAKDK AAVIVIIIGV RNKSNNSKKI YEGNHVRVVS
     NINPYLTTGN SSYITRRSKP ISPQLQKIVY GNLINDNGNL VLNESEKCEL MRKYPLTENY
     IKLYIGSKEY LRGETRYCLY IEDDELQNAI QIPEIKKRLD AIRVHRANSS EKSTKALAPF
     PNRFYFQSYN NTESIIIPRT SSENREYIPI GFLSSNIIIS DAAQAIYEAK PWVFGIISSR
     MHMTWVRAVA GRLKSDYRYS SAICYNTFPF PPITETQKKE LEKHTYRVLE ERENHSEKTL
     AQLYNPDKMP DGLREAHHQL DLAVERCYRA KPFETDEERL EYLFKLYEQM IEEEKSKGSL
     FESEAKPKKK KK
//