ID   Q3C0H8_LOTJA            Unreviewed;      1508 AA.
AC   Q3C0H8;
DT   22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2005, sequence version 1.
DT   27-MAR-2024, entry version 70.
DE   RecName: Full=Reverse transcriptase {ECO:0008006|Google:ProtNLM};
OS   Lotus japonicus (Lotus corniculatus var. japonicus).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; Hologalegina; robinioid clade; Loteae; Lotus.
OX   NCBI_TaxID=34305 {ECO:0000313|EMBL:CAJ00277.1};
RN   [1] {ECO:0000313|EMBL:CAJ00277.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Madsen L.H., Fukai E., Radutoiu S., Yost C.K., Sandal N., Schauser L.,
RA   Stougaard J.;
RT   "LORE1, an active low-copy-number TY3-gypsy retrotransposon family in the
RT   model legume Lotus japonicus.";
RL   Plant J. 44:372-381(2005).
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DR   EMBL; AJ966994; CAJ00277.1; -; Genomic_DNA.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd00303; retropepsin_like; 1.
DR   CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 1.10.340.70; -; 1.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR016197; Chromo-like_dom_sf.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR041588; Integrase_H2C2.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041577; RT_RNaseH_2.
DR   PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR   Pfam; PF17921; Integrase_H2C2; 1.
DR   Pfam; PF17919; RT_RNaseH_2; 1.
DR   Pfam; PF00665; rve; 1.
DR   Pfam; PF08284; RVP_2; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF50630; Acid proteases; 1.
DR   SUPFAM; SSF54160; Chromo domain-like; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
FT   DOMAIN          621..800
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   DOMAIN          1139..1303
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
SQ   SEQUENCE   1508 AA;  171466 MW;  82EDA6E32A22A7EF CRC64;
     MAEATRFQSS IREAEERIMA AMDPCIARHM RELELRFETQ FNGFQEAMRG IGLQVTDLAS
     ARRSRTPGDG DHRMPTRLTR LDFPKFSKDD VDSWIAKCER FFALDGTPEG ERVAVASIAM
     DESSFRWFQG LEQGTVGRVT WPEFAAALRT RFGVEFESPM EELKRLVQQG NLEEYHEAFD
     NLACRTELSE SLKLQCYLGG LNPELCTGVK MFGPRTLLEA MRIAKLQERS LELLHKKSNS
     VTKTYSNWSE RKGVAPVTVE KKAIERKTVR ENNQEGILGK PNYTFQKKLT PKEMDEHRTQ
     NLCFFCHEKY TPGHDCPQRK KSQVFFMAVD GLESEELLEE VEQESRPEVN VPKVSLNALH
     GDSISLDALD GDSEYPMMRL TGWLGKKRIF VLIDTGSTHN FINQKLCHEG LSKIKCLQPV
     KITVADGGII QGTGWCEGIS WKMQGYTFTD NAIAIPLSSC DLILGMQWLR QRGKISWDFT
     NLIMEFAMGT EMVRLQAMEE KENKLVTAAK LHHMVGEDKF SFLLQILPCF QEVACCTIKA
     TESGNSGLSS EGGNEELQAH KEAILQDYSD VFEEPAQLPP FRGIHDHKII LKEGSNPVSL
     RPYRYPPAQK DVIDKMVKEL LESGVIQPSS SPFASPIVLV KKKDGSWRMC VDYRKLNDMT
     VKAKFPIPLV EYLLDELGGA KIFSKLDLRA GYHQLRMRPE DVEKTAFQTH SGQYEYVVMP
     FGLTNAPSTF QGAMNAIFAP FLRKSVLIFF DDILVYSATV EAHLQHLREV FAVLRKHSFY
     VKRSKCAFFT PVIEYLGHFI SASGVSTDST KIKAIQDWPE PVTIKQLRGF LGLTGYYRRF
     IKGYSILASP LTDLLRKDGF HWSAAASAAF LQLKNALVQA PVLAIPDLQK PFTVETDASS
     TGIGAVLLQD KHPVAFISKV LSPRNRLLSV YDRELLALVH AVTKWHQYLA IQQFTILTDQ
     QSLKFLLEQR LSTPAQYRWV TKLMGLSYVI QYKRGKENVV ADALSRASHG ELFQLSVSSI
     SSELGGLLTQ AYAADEALQQ LISQVLAQPQ LHAHYSVVDG FLFRKHRLMI PNNSQVRTLI
     LEWLHSSHQG GHSGIRATVV RIKSLFFWKG LSKDVADFIQ KCETCLRCKY ERVASPGLLQ
     PLPIPAGVWQ SIAMDFIDKL PKSHGKDAIW VVIDRLSKYA HFIPLTHPYT ASTLAEIFIK
     EVYRLHGAPS NIVSDRDPLF TSTFWTAFLQ QLGISQSLTT AYHPQSDGQS EVLNRCLEHY
     LRAMTWQRPK EWVTWLPLAE WWYNTTYHSA IQTTPYEVVY GQPPAIHLPY CPQSTIVEAV
     DRSFTAREQM IQKLHANLMR AQARMKIQAD KHRTDREFSV GDWVLLKLQP YRQSSTQHRA
     SEKLSPRFFG PYQVLHRVGK VAYTLALPPE SKIHPTFHVS LLKPCPSPAM PHVPLPLEWG
     NLDQPKAPFK ILKRRMVQRR HKAVTEVLVQ WLGEMEEEAT WEVLYNLKLK YPTFDTTVVV
     PENSRVIP
//