ID Q3HV71_SHEEP Unreviewed; 104 AA.
AC Q3HV71;
DT 08-NOV-2005, integrated into UniProtKB/TrEMBL.
DT 08-NOV-2005, sequence version 1.
DT 24-JAN-2024, entry version 63.
DE SubName: Full=Bone morphogenic protein 6 {ECO:0000313|EMBL:ABA41491.1};
DE Flags: Fragment;
GN Name=BMP6 {ECO:0000313|EMBL:ABA41491.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|EMBL:ABA41491.1};
RN [1] {ECO:0000313|EMBL:ABA41491.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Ovary {ECO:0000313|EMBL:ABA41491.1};
RX PubMed=16514193; DOI=10.1530/rep.1.00958;
RA Juengel J.L., Reader K.L., Bibby A.H., Lun S., Ross I., Haydon L.J.,
RA McNatty K.P.;
RT "The role of bone morphogenetic proteins 2, 4, 6 and 7 during ovarian
RT follicular development in sheep: contrast to rat.";
RL Reproduction 131:501-513(2006).
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DQ192014; ABA41491.1; -; mRNA.
DR AlphaFoldDB; Q3HV71; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF137; BONE MORPHOGENETIC PROTEIN 6; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR PRINTS; PR00669; INHIBINA.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354}; Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 1..104
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABA41491.1"
FT NON_TER 104
FT /evidence="ECO:0000313|EMBL:ABA41491.1"
SQ SEQUENCE 104 AA; 11826 MW; 75AB983A05EE5CBB CRC64;
SSELKTACRK HELYVSFQDL GWQDWIIAPK GYAANYCDGE CSFPLNAHMN ATNHAIVQTL
VHLMNPEYVP KPCCASTKLN AISVLYFDDN SNVILKKYRN MVVR
//
