ID Q3MQB4_HBV Unreviewed; 210 AA.
AC Q3MQB4;
DT 25-OCT-2005, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2005, sequence version 1.
DT 14-DEC-2022, entry version 55.
DE SubName: Full=Reverse transcriptase {ECO:0000313|EMBL:CAJ27080.1};
DE Flags: Fragment;
GN Name=rt {ECO:0000313|EMBL:CAJ27080.1};
OS Hepatitis B virus (HBV).
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Blubervirales; Hepadnaviridae; Orthohepadnavirus.
OX NCBI_TaxID=10407 {ECO:0000313|EMBL:CAJ27080.1};
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9598; Pan troglodytes (Chimpanzee).
RN [1] {ECO:0000313|EMBL:CAJ27080.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HM-HBVrt-pt4-11-6 {ECO:0000313|EMBL:CAJ27080.1};
RX PubMed=16378967; DOI=10.1128/JVI.80.2.643-653.2006;
RA Pallier C., Castera L., Soulier A., Hezode C., Nordmann P., Dhumeaux D.,
RA Pawlotsky J.M.;
RT "Dynamics of hepatitis B virus resistance to lamivudine.";
RL J. Virol. 80:643-653(2006).
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DR EMBL; AM073943; CAJ27080.1; -; Genomic_DNA.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022918,
KW ECO:0000313|EMBL:CAJ27080.1}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..189
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAJ27080.1"
FT NON_TER 210
FT /evidence="ECO:0000313|EMBL:CAJ27080.1"
SQ SEQUENCE 210 AA; 23740 MW; 07C698C5DD987EC6 CRC64;
LQSLTNLLSS NLSWLSLDVS AAFYHIPLHP AAMPHLLIGS SGLSRYVARL SSNSRINNNQ
YGTMQNLHDS CSRQLYVSLM LLYKTYGWKL HLYSHPIVLG FRKIPMGLGL SPFLLAQFTS
AICSVVRRAF PHCLAFSYID DIVLGAKSVQ HRESLYTAVT NFLLSLGIHL NPNKTKRWGY
SLNFMGYIIG SWGTLPQDHI VQKIKHCFRK
//
