ID Q3SIL9_THIDA Unreviewed; 615 AA.
AC Q3SIL9;
DT 11-OCT-2005, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2005, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Oxaloacetate decarboxylase, alpha subunit {ECO:0000313|EMBL:AAZ97509.1};
GN OrderedLocusNames=Tbd_1556 {ECO:0000313|EMBL:AAZ97509.1};
OS Thiobacillus denitrificans (strain ATCC 25259).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Thiobacillaceae; Thiobacillus.
OX NCBI_TaxID=292415 {ECO:0000313|EMBL:AAZ97509.1, ECO:0000313|Proteomes:UP000008291};
RN [1] {ECO:0000313|EMBL:AAZ97509.1, ECO:0000313|Proteomes:UP000008291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25259 {ECO:0000313|EMBL:AAZ97509.1,
RC ECO:0000313|Proteomes:UP000008291};
RX PubMed=16452431; DOI=10.1128/JB.188.4.1473-1488.2006;
RA Beller H.R., Chain P.S., Letain T.E., Chakicherla A., Larimer F.W.,
RA Richardson P.M., Coleman M.A., Wood A.P., Kelly D.P.;
RT "The genome sequence of the obligately chemolithoautotrophic, facultatively
RT anaerobic bacterium Thiobacillus denitrificans.";
RL J. Bacteriol. 188:1473-1488(2006).
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DR EMBL; CP000116; AAZ97509.1; -; Genomic_DNA.
DR RefSeq; WP_011312068.1; NC_007404.1.
DR AlphaFoldDB; Q3SIL9; -.
DR STRING; 292415.Tbd_1556; -.
DR KEGG; tbd:Tbd_1556; -.
DR eggNOG; COG0511; Bacteria.
DR eggNOG; COG5016; Bacteria.
DR HOGENOM; CLU_000395_4_2_4; -.
DR OrthoDB; 9760256at2; -.
DR Proteomes; UP000008291; Chromosome.
DR GO; GO:0008948; F:oxaloacetate decarboxylase activity; IEA:InterPro.
DR GO; GO:0004736; F:pyruvate carboxylase activity; IEA:UniProt.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR CDD; cd06850; biotinyl_domain; 1.
DR CDD; cd07937; DRE_TIM_PC_TC_5S; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR001882; Biotin_BS.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR003379; Carboxylase_cons_dom.
DR InterPro; IPR005776; OadA.
DR InterPro; IPR000891; PYR_CT.
DR InterPro; IPR011053; Single_hybrid_motif.
DR NCBIfam; TIGR01108; oadA; 1.
DR PANTHER; PTHR45266; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR PANTHER; PTHR45266:SF3; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR Pfam; PF02436; PYC_OADA; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR SUPFAM; SSF89000; post-HMGL domain-like; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS00188; BIOTIN; 1.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 4: Predicted;
KW Biotin {ECO:0000256|ARBA:ARBA00023267};
KW Reference proteome {ECO:0000313|Proteomes:UP000008291}.
FT DOMAIN 4..264
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
FT DOMAIN 538..613
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
FT REGION 516..543
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 615 AA; 66477 MW; 40839E79E68B49E6 CRC64;
MNKVFVTDLV LRDGHQSLIA TRMRTEDMLP ICGKLDQVGF WSLEAWGGAT FDACVRFLRE
DPWERLRKLR KALPNTPIQM LLRGQNLLGY RNYSDDVVRA FVQKSADNGV DVFRVFDAMN
DVRNLRVSIE AVKAAGKHAE GAISYTTSPV HDIPHFVTLA RGLAEMGCDT IAIKDMAGLL
TPYTAYDLVC AIREATHLPI HTHSHATSGL AHMTHLKAVE AGATIIDTSV GAFAEGASHP
TTQSLVAALA GTAYDTGLSL PLIEEISAYF KDVRKKYWQF ESAFTGTDTR VLINQVPGGM
ISNLANQLKE QGALDKMDAV LEEIPRVRED LGYPPLVTPT SQIVGTQAAL NVLTGARYKS
VTNEVKLYLQ GRYGRAPGHV NEEVRKMAIG DLDVTTGRPA DLLGDELDKL RGEIEGLAKS
DEDVLTYAMF PEIGKTWLQE RAAGSLKPEP LLPPGATEQA STTRYAADEF KVTLHGETYH
IKLSGSGRSE AAQRPYFVSI DGVSEEVLVE PLNEVPLSGG ADTPRKLPAE AASAPGEKPR
ARHPGHVTAA MPGNVVDVLV SVGQTVQAGD GVLVIEAMKM ESEVQAPIAG VVINLFAKKG
DAVTPDMALV EIQPA
//
