ID   Q3YLC5_9HYPO            Unreviewed;       345 AA.
AC   Q3YLC5;
DT   27-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2005, sequence version 1.
DT   27-MAR-2024, entry version 69.
DE   RecName: Full=chitinase {ECO:0000256|ARBA:ARBA00012729};
DE            EC=3.2.1.14 {ECO:0000256|ARBA:ARBA00012729};
OS   Cordyceps javanica.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Cordycipitaceae; Cordyceps.
OX   NCBI_TaxID=43265 {ECO:0000313|EMBL:AAZ83728.1};
RN   [1] {ECO:0000313|EMBL:AAZ83728.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=17551789; DOI=10.1007/s00284-006-0405-y;
RA   Chen C.-C., Kumar H.G., Kumar S., Tzean S.S., Yeh K.-W.;
RT   "Molecular cloning, characterization, and expression of a chitinase from
RT   the entomopathogenic fungus Paecilomyces javanicus.";
RL   Curr. Microbiol. 55:8-13(2007).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide
CC         (1->4)-beta-linkages in chitin and chitodextrins.; EC=3.2.1.14;
CC         Evidence={ECO:0000256|ARBA:ARBA00000822};
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family. Chitinase
CC       class V subfamily. {ECO:0000256|ARBA:ARBA00008682}.
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DR   EMBL; DQ092417; AAZ83728.1; -; mRNA.
DR   AlphaFoldDB; Q3YLC5; -.
DR   SMR; Q3YLC5; -.
DR   CAZy; GH18; Glycoside Hydrolase Family 18.
DR   CLAE; CHI18C_ISAJA; -.
DR   BRENDA; 3.2.1.14; 9473.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR   GO; GO:0004568; F:chitinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006032; P:chitin catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR   CDD; cd06548; GH18_chitinase; 1.
DR   Gene3D; 3.10.50.10; -; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR011583; Chitinase_II.
DR   InterPro; IPR029070; Chitinase_insertion_sf.
DR   InterPro; IPR001223; Glyco_hydro18_cat.
DR   InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR11177; CHITINASE; 1.
DR   PANTHER; PTHR11177:SF365; ENDOCHITINASE B; 1.
DR   Pfam; PF00704; Glyco_hydro_18; 1.
DR   SMART; SM00636; Glyco_18; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR   PROSITE; PS01095; GH18_1; 1.
DR   PROSITE; PS51910; GH18_2; 1.
PE   2: Evidence at transcript level;
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW   Chitin degradation {ECO:0000256|ARBA:ARBA00023024};
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW   Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT   DOMAIN          1..318
FT                   /note="GH18"
FT                   /evidence="ECO:0000259|PROSITE:PS51910"
SQ   SEQUENCE   345 AA;  38433 MW;  ABE7574FB9CF6DD5 CRC64;
     MTDEWADTGI HWEGDSWNDT GNNMYGCLKQ LNLLKRRNRN LKLLLSIGGW TYSSNFKVPA
     SSPQGRSTFA KTSVELLKKY GFDGIDIDWE YPTNPNEARN FVELLAEVRR ELDAYSQQLG
     NGFHFEITVA CPAGPQNFNN MDIAGMDRFL DFWNLMAYDY AGSWDRVSGH QANLFPSRNN
     PASTPFSTVA AVDHYVRSGV RPDKIVLGMP LYGRAFENTG GPGQPFQGVG EGTWEQGVHD
     YKKLPLPGTQ EMYDEAAGAT YCYGQGKMVS YDTPGMARQK TDYIKQRGLG GAMWWESSSD
     KQGPDSLIGT VVNSFGGPGG LLRTNNCLEY PQTPYDNLRD GFPNN
//