ID Q400H3_THECA Unreviewed; 355 AA.
AC Q400H3;
DT 27-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2005, sequence version 1.
DT 13-SEP-2023, entry version 35.
DE SubName: Full=Glucose-1-phosphate thymidylyltransferase {ECO:0000313|EMBL:CAE53846.1};
DE EC=2.7.7.24 {ECO:0000313|EMBL:CAE53846.1};
GN Name=rmlA {ECO:0000313|EMBL:CAE53846.1};
OS Thermus caldophilus.
OC Bacteria; Deinococcota; Deinococci; Thermales; Thermaceae; Thermus.
OX NCBI_TaxID=272 {ECO:0000313|EMBL:CAE53846.1};
RN [1] {ECO:0000313|EMBL:CAE53846.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GK24 {ECO:0000313|EMBL:CAE53846.1};
RA Parajuli N., Basnet D.B., Chung Y.S., Lee H.C., Liou K., Sohng J.K.;
RT "Biochemical characterization of a novel thermostable glucose-1-phosphate
RT thymidylyltransferase from Thermuscaldophilus: Probing the molecular basis
RT for its unusual thermostability.";
RL Enzyme Microb. Technol. 37:402-409(2005).
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DR EMBL; AJ605742; CAE53846.1; -; Genomic_DNA.
DR AlphaFoldDB; Q400H3; -.
DR BRENDA; 2.7.7.24; 6330.
DR GO; GO:0008879; F:glucose-1-phosphate thymidylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd04189; G1P_TT_long; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR InterPro; IPR005908; G1P_thy_trans_l.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR NCBIfam; TIGR01208; rmlA_long; 1.
DR PANTHER; PTHR42883; GLUCOSE-1-PHOSPHATE THYMIDYLTRANSFERASE; 1.
DR PANTHER; PTHR42883:SF2; ZGC:136439; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:CAE53846.1};
KW Transferase {ECO:0000313|EMBL:CAE53846.1}.
FT DOMAIN 2..235
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 355 AA; 38093 MW; ED4D09D1E3693E11 CRC64;
MKALVLSGGA GTRLRPITHT SAKQLVPVAN KPVLFYGLES LADAGITDVG MIVGDTAAEI
EEAVGDGSAF GLKVTYIPQE QPLGLAHAVL IARDWLGDDD FVMYLGDNFI VGGITGLVDE
FRRHRPDAQI LLTRVADPRS FGVAELDASG QVIGLEEKPD DPKSDLALVG VYLFTPAIHD
AVRAIRPSWR GELEITHAIQ HLIDARADVR CTVIHGYWKD TGNVVDMLEV NRSVLEGLDR
RIDGDIDDDS EAIGRVVVEE GARIVGSRIV GPAVIAAGTV VTHSYIGPFT SVAENCRITD
SEVEFSIVLR DSSIDGVSRI EASLIGRHVE VTPAPSVPSA HRLVLGDHSK VQIHT
//
