ID Q46LQ8_PROMT Unreviewed; 314 AA.
AC Q46LQ8;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=Radical SAM protein {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=PMN2A_0078 {ECO:0000313|EMBL:AAZ57570.1};
OS Prochlorococcus marinus (strain NATL2A).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales;
OC Prochlorococcaceae; Prochlorococcus.
OX NCBI_TaxID=59920 {ECO:0000313|EMBL:AAZ57570.1, ECO:0000313|Proteomes:UP000002535};
RN [1] {ECO:0000313|EMBL:AAZ57570.1, ECO:0000313|Proteomes:UP000002535}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NATL2A {ECO:0000313|EMBL:AAZ57570.1,
RC ECO:0000313|Proteomes:UP000002535};
RX PubMed=18159947; DOI=10.1371/journal.pgen.0030231;
RA Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S.,
RA Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M.,
RA Richardson P., Chisholm S.W.;
RT "Patterns and implications of gene gain and loss in the evolution of
RT Prochlorococcus.";
RL PLoS Genet. 3:2515-2528(2007).
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DR EMBL; CP000095; AAZ57570.1; -; Genomic_DNA.
DR RefSeq; WP_011293612.1; NC_007335.2.
DR AlphaFoldDB; Q46LQ8; -.
DR STRING; 59920.PMN2A_0078; -.
DR KEGG; pmn:PMN2A_0078; -.
DR HOGENOM; CLU_050695_0_0_3; -.
DR OrthoDB; 9810775at2; -.
DR PhylomeDB; Q46LQ8; -.
DR Proteomes; UP000002535; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR024521; ArsS-like_C.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR026351; rSAM_ArsS-like.
DR NCBIfam; TIGR04167; rSAM_SeCys; 1.
DR PANTHER; PTHR43728:SF1; RADICAL SAM SUPERFAMILY PROTEIN-RELATED; 1.
DR PANTHER; PTHR43728; SLR0304 PROTEIN; 1.
DR Pfam; PF12345; DUF3641; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002535};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 21..158
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|Pfam:PF04055"
FT DOMAIN 177..311
FT /note="Arsenosugar biosynthesis radical SAM protein ArsS-
FT like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12345"
SQ SEQUENCE 314 AA; 35348 MW; 065B7CD187F1826A CRC64;
MEIIKKKFPK IKRDYLDTLQ INIGYKCNQA CSHCHVDSSP SRTEMMSDDI IKLIPKVIKA
NEIKLLDITG GAPELHPKFK QLVIEVRSLN VEVMDRCNLT ILKEPGYESL AGFLASNKVQ
ITASLPCYLE GNVDKQRGKG VFEKSILALK QLNNLGYGIK DKGLLLNLVY NPSTPQLPPS
QKELEDIYRR ELKERYGIFF SNLYVLANMP INRYENYLKT IGKLEEYNKL LKDNHNPGNI
NSVMCRSTLS VDWKGFLYDC DFNQQLGMKR NGNVKHLNDL LIPLVSLKNN PISTGNHCFG
CTAGAGSSCG GELT
//
