ID Q46U27_CUPPJ Unreviewed; 585 AA.
AC Q46U27;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer {ECO:0000313|EMBL:AAZ63357.1};
GN OrderedLocusNames=Reut_B4001 {ECO:0000313|EMBL:AAZ63357.1};
OS Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Cupriavidus necator
OS (strain JMP 134)).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=264198 {ECO:0000313|EMBL:AAZ63357.1};
RN [1] {ECO:0000313|EMBL:AAZ63357.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JMP134 {ECO:0000313|EMBL:AAZ63357.1};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M., Schmutz J.,
RA Larimer F., Land M., Lykidis A., Richardson P.;
RT "Complete sequence of chromosome 2 of Ralstonia eutropha JMP134.";
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP000091; AAZ63357.1; -; Genomic_DNA.
DR AlphaFoldDB; Q46U27; -.
DR STRING; 264198.Reut_B4001; -.
DR KEGG; reu:Reut_B4001; -.
DR eggNOG; COG0840; Bacteria.
DR HOGENOM; CLU_000445_107_16_4; -.
DR OrthoDB; 8555762at2; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd11386; MCP_signal; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR033480; sCache_2.
DR PANTHER; PTHR43531:SF14; METHYL-ACCEPTING CHEMOTAXIS PROTEIN I-RELATED; 1.
DR PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR Pfam; PF17200; sCache_2; 1.
DR PRINTS; PR00260; CHEMTRNSDUCR.
DR SMART; SM01049; Cache_2; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:AAZ63357.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW Transferase {ECO:0000313|EMBL:AAZ63357.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 270..499
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT REGION 521..585
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 470..508
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 531..552
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 585 AA; 61985 MW; B426BBD10B4FF899 CRC64;
MKTLTLNQRL WIPFGLIWIA MLGICTYEAF VTRAEMFAGR QREIQSVAEA SVSLVAAIEK
EAASEGLSVE EAQKLAKERL RPLRFGTDGY VSITDFSGRS LMHPFKPENE GKNLSTMKDP
NGVLIYVEIA KIASGQGAGF LNYMWPKPGA SQPLPKVSYV KAFKTWEWTV TTGAYVDDIE
AAFRQALLHS ILTLVILGGA ATVLAAWLLR GVRRDLGGEP AYAASVANSI ADGDFTRDID
VRPGDTSSLL FAMQRMQRKL GGTVSGIRAS VDSVATATAQ IAAGNSDLSS RTEQQAASLQ
ETAASMEELT TTVQHNADSA RQASGLADNA SEIANRGGEV MEQVITTMTQ IADSSSQIAD
IIGVIEGIAF QTNILALNAA VEAARAGEQG RGFAVVAGEV RSLAQRSAGA AKEIRTLIST
SVDRVRSGSD LVERAGSTMT EITQSIRRVT DIMGEIAAAS VEQRTGIEQV NQAVAQMDQV
TQQNAALVEE ATAAAHSLEE QAAALRQSVA AFRVAQHGGG GAAVVHQPAP APRRPAAPKA
EPVLPQVPKA PKAPKAPKAL KALKAQPARA ARTESADAGD NWEQF
//
