ID Q47RL1_THEFY Unreviewed; 451 AA.
AC Q47RL1;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 121.
DE SubName: Full=Chitinase. Glycosyl Hydrolase family 18 {ECO:0000313|EMBL:AAZ54906.1};
DE EC=3.2.1.14 {ECO:0000313|EMBL:AAZ54906.1};
GN OrderedLocusNames=Tfu_0868 {ECO:0000313|EMBL:AAZ54906.1};
OS Thermobifida fusca (strain YX).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Thermobifida.
OX NCBI_TaxID=269800 {ECO:0000313|EMBL:AAZ54906.1};
RN [1] {ECO:0000313|EMBL:AAZ54906.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=YX {ECO:0000313|EMBL:AAZ54906.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Di Bartolo G., Chain P., Schmutz J.,
RA Larimer F., Land M., Lykidis A., Richardson P.;
RT "Complete sequence of Thermobifida fusca YX.";
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family.
CC {ECO:0000256|RuleBase:RU004453}.
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DR EMBL; CP000088; AAZ54906.1; -; Genomic_DNA.
DR AlphaFoldDB; Q47RL1; -.
DR STRING; 269800.Tfu_0868; -.
DR CAZy; GH18; Glycoside Hydrolase Family 18.
DR KEGG; tfu:Tfu_0868; -.
DR eggNOG; COG3325; Bacteria.
DR HOGENOM; CLU_002833_14_4_11; -.
DR OrthoDB; 9775889at2; -.
DR BRENDA; 3.2.1.200; 6298.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR GO; GO:0004568; F:chitinase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06548; GH18_chitinase; 1.
DR Gene3D; 3.10.50.10; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR011583; Chitinase_II.
DR InterPro; IPR029070; Chitinase_insertion_sf.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR11177; CHITINASE; 1.
DR PANTHER; PTHR11177:SF317; CHITINASE 11; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR SMART; SM00636; Glyco_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 52..451
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
SQ SEQUENCE 451 AA; 50626 MW; 0E2E4F2744DE259F CRC64;
MAGRHRILPA RRRTFAPTWV VLLVAAGVVA LCGGVVVLLG PRLGNWWTRP TAERIAYFAD
WNTANRGYTI KDVDESGAAA LLDRLIWAFG DVSEDGLCHI PAEADQPWQI FQRRYEAAES
VDGQADTYEQ PLAGSLNQLR KLQQKYPDLR ASISLGGWNW STYFSEAVRT QESRERFVAS
CIDLWLRGNL PRLEGEPQGG EGVAAGIFDG IDLDWEWPGG NGHPDNVEHP DDKRNFTLVV
QEFRAQLDAL ERETGREYTL SASLSHDPKI MRDSYEPEVF DYLDFATVQG YDFTGSWRDI
TGHHAQLYAP DQDPDQPSVD RAVRQYLDYG LPAEKLVLGI PGYGRGWRGV PPGPNGDGWL
VEAEQPAEGG YGEATHAYET LEQHPGERFF DRETGAAWIY DGDEWWSYDT PEVVRRKGAY
AVRHGLRGLV LWNLDMDPEG ELVAAMAESL R
//
